Activation of PPARγ induces the expression of lipogenic genes, such as adipocyte fatty acid binding protein (aP2), and of lipolytic genes, such as hormone-sensitive lipase (HSL) [3]. ❋ Unknown (2009)
In cell culture studies, curcumin supressed preadipocyte differentiation, promoted adipocyte apoptosis (programmed cell death) and inhibited growth of adipokine-stimulated angiogenesis. ❋ Unknown (2009)
Another great post - I particularly like the discussion of the potential health benefit of adipocyte hyperplasia. ❋ Unknown (2009)
Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner. ❋ Dr. Mike Moreno (2010)
These impairments correlated with critical clinical measures of obesity including liver fat accumulation, reduced whole-body insulin sensitivity, hyperinsulinemia, hypoadiponectinemia and adipocyte hypertrophy. ❋ Unknown (2008)
Obesity has often been described as a state of “leptin resistance” - i.e. despite having elevated circulating levels of leptin, an adipocyte-derived “appetite inhibitor”, obese patients continue to consume calories in excess of their metabolic needs. ❋ Unknown (2008)
On another note, Metabolic Syndrome, abdominal obese patients have insulin resistance, but is it at the whole body level liver, muscle, and adipocyte, or only at the muscle and liver? ❋ Unknown (2008)
There is no natural mechanism for killing excessive fat cells, because having massive pockets of insulin-stimulated adipocyte hyperplasia is not a natural condition. ❋ Unknown (2008)
Nichols AM, Pan Y, Herreman A, Hadland BK, De Strooper B, et al. (2004) Notch pathway is dispensable for adipocyte specification. ❋ Alexis Dumortier Et Al. (2010)
In the study, Slimaluma reduced pre-adipocyte cell division by up to 35%. ❋ Amp;34; (2010)
Thus fMSCs represent a useful in vitro model for human adipogenesis, and provide opportunities to study the stages prior to commitment to the adipocyte lineage. ❋ Daniel L Morganstein (2010)
Knowing that canonical Notch signaling is dispensable for adipocyte specification ❋ Alexis Dumortier Et Al. (2010)
In a laboratory study, the key component in DEX-C20 reduced pre-adipocyte cell division by up to 35%. 3 ❋ Amp;34; (2010)
We showed that the expression of key adipocyte regulators and markers during differentiation is similar to that in other human and murine adipocyte models, including induction of PPAR γ2 and FABP4. ❋ Daniel L Morganstein (2010)
Our current research centers on the function of histone modifications and their corresponding modifying enzymes in adipocyte differentiation. ❋ Unknown (2010)
Areas of current expertise within the Division include adipocyte biology, in vivo murine metabolic physiology, ❋ Unknown (2010)
To fully decipher the epigenetic mechanisms controlling adipocyte lineage commitment and differentiation, we utilize the advanced genomic and proteomic methodologies as well as classic biochemistry and molecular biology techniques in our study. ❋ Unknown (2010)
Insulin is the major antilipolytic hormone because of itseffects on enzymes within the adipocyte. ❋ Amp;34;Weight Loss (2010)
DEX-C20 reduced pre-adipocyte cell division by up to 35%. 3 ❋ Amp;34; (2010)
