In a moment of pure scientific inspiration, Pauling inductively determined the three-dimensional geometry of the alpha-helix — one of the fundamental units of protein structure — while lying in bed sick in Oxford. ❋ Nick Anthis (2006)
By using bioinformatic and biochemical analyses, we showed that residues 1-18 of FliI very likely form an amphipathic alpha-helix upon interaction with FliH, and that residues 21-91 of FliI resemble the N-terminal oligomerization domain of the F1-ATPase catalytic subunits. ❋ Unknown (2006)
The interaction between FliI and FliH has similarities to the interaction between the N-terminal alpha-helix of the F1-ATPase alpha-subunit and the globular domain of the F1-ATPase delta-subunit, respectively. ❋ Unknown (2006)
By the look of it, the FliC protein has loads of alpha-helix and no beta-sheet, which is rather different from the FliI protein. ❋ Unknown (2007)
It turns out that one of the biochemical differences is that Subtype B Vps have a Golgi retention signal in the second alpha-helix of the cytoplasmic domain.13 This means that Subtypes B Vpu prefers if you will excuse me personifying a virus to be in the Golgi, helping degrade CD4, while Subtype C Vpu prefers to be in the plasma membrane, assisting with the release of new viruses. ❋ Unknown (2007)
It has thus become apparent that one of these structures, the so-called alpha-helix, probably exists in several proteins. ❋ Unknown (1964)
By screening a library of stabilized alpha-helix of BCL-2 domains (SAHBs), we determined that the MCL-1 BH3 helix is itself a potent and exclusive MCL-1 inhibitor. ❋ Michelle L Stewart (2010)
"A PUR repeat looks like a hand: four so-called beta-strands, corresponding to four fingers, form a beta-sheet, and an adjacent alpha-helix resembles a thumb", explains Almut Graebsch, the first author from Niessing's group. ❋ Unknown (2009)
The norleucine variant resulted in an alpha-helix rich protein that lacks the in vitro aggregation protein of the parent protein. ❋ Unknown (2009)
The distribution of mutations identifies one side of the Sbh1p trans-membrane domain alpha-helix that is involved in interactions with Sec61p and that is important for Sbh1p function in protein translocation. ❋ Unknown (2009)
It turns out that one of the biochemical differences is that Subtype B Vps have a Golgi retention signal in the second alpha-helix of the cytoplasmic domain 13. ❋ Unknown (2009)
Lavander M, Sjöstedt A (2009) A conserved alpha-helix essential for a type VI secretion-like system of ❋ Konstantin Kadzhaev Et Al. (2009)
Pictures of alpha-helix and beta-sheet, simple DNA or RNA with phophate bonds, and some oil-based polymers would greatly aid the reader in understanding a monomer within a polymer. ❋ Unknown (2009)
"A PUR repeat looks like a hand: four so-called beta-strands, corresponding to four fingers, form a beta-sheet, and an adjacent alpha-helix resembles a thumb," explains Almut Graebsch, the first author from Niessing's group.
The effects of beta-branched residues on alpha-helix stability have been intensively studied and shown to destabilize helix propensity ❋ Unknown (2009)
The color change occurs when the blue light causes the protein's flavin cofactor to form a reversible bond with a cysteine residue on the nearby alpha-helix. ❋ Unknown (2009)
