Anaphase

Seldom has the word "anaphase" held more suppressed longing. ❋ Sam Adams (2011)

In the current study, the investigators found that when cancer cells with extra centrosomes enter "anaphase" - the stage of cell division when chromosomes move toward the poles of the spindle before being drawn into the new daughter cells - a few chromosomes lagged behind the others. ❋ Unknown (2009)

The metaphase-anaphase transition is orchestrated through proteolysis of numerous proteins by a ubiquitin protein ligase called the anaphase-promoting complex or cyclosome (APC/C). ❋ Raquel A. Oliveira (2010)

It also reported that inhibition of CDK2 by seliciclib suppressed lung cancer growth both in vitro and in vivo of lung cancer cells addicted to CDK2/cyclin E; and lung cancer cells underwent apoptosis or cell suicide by induction of a novel mechanism called anaphase catastrophe, as illustrated in the journal's front cover. ❋ Unknown (2010)

This resulted in the identification of two ubiquitin-protein ligase complexes: the cyclosome, now also called anaphase-promoting complex or APC / C, involved in the degradation of mitotic cyclins and some other cell cycle regulatory proteins in exit from mitosis ❋ Unknown (2009)

The E3 enzyme responsible, a protein complex termed the "anaphase-promoting complex" (APC) checks that the cell goes out of mitosis. ❋ Unknown (2004)

A rise in intracellular calcium at the onset of anaphase could regulate the polar ejection force by shutting down the centriolar turbines, but defective regulation could result in an excessive force that contributes to the chromosomal instability characteristic of most cancer cells. ❋ Unknown (2005)

It should be possible to test this by observing chromosome behavior in the spindles of dividing animal cells while artificially raising the concentration of intracellular calcium during prometaphase or blocking its rise at the beginning of anaphase. ❋ Denyse O (2005)

In contrast, 82.5% of injected cells align chromosomes in metaphase, progress to anaphase, and display chromosome velocities not significantly different from control cells. ❋ Unknown (2005)

But today I could barely talk, coughing up reams of horrifying crap, and even writing this sentence is taking all the late-anaphase mitosis I can muster. ❋ Unknown (2003)

The rupture occurred, in the first instance, at a meiotic anaphase in each parent, and the ruptured end then underwent the succession of mitotic anaphase breaks associated with the chromatid type of breakage-fusion-bridge cycle during the development of the male and female gametophytes -- the pollen grain and the embryo sac. ❋ Unknown (1983)

The two chromatids produced by the replication process appeared to be fused at the loaction of the break that had occurred at the previous meiotic anaphase. ❋ Unknown (1983)

The following was noted: (1) In the majority of mitoses replication of the ring chromosome produced two chromatids that were completely free from each other and thus could separate without difficulty in the following anaphase. ❋ Unknown (1983)

In the following anaphase, passage of the centromeres to opposite poles would produce two chromatid bridges. ❋ Unknown (1983)

At the meiotic anaphase, passage of the two centromeres of the dicentric chromosome to opposite poles of the spindle produces a bridge. ❋ Unknown (1983)

It was soon learned that the chromatid type of breakage-fusion-bridge cycle, initiated at a meiotic anaphase, will continue during the development of the pollen grain and the embryo sac. ❋ Unknown (1983)

This is because the location of breaks in some of the anaphase bridges gave rise to chromosomes with at least a full complement of genes necessary for pollen functioning. ❋ Unknown (1983)

A chromatin bridge would form at the meiotic anaphase by passage of the two centromeres on the dicentric chromosome to opposite poles of the spindle. ❋ Unknown (1983)

[I'm going to] digital anaphase [your black] [ass]. ❋ Yer916 (2005)