Anticonvulsant Wiki - What is the anticonvulsant?
Anticonvulsants (also commonly known as antiepileptic drugs or as antiseizure drugs) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. Anticonvulsants are also increasingly being used in the treatment of bipolar disorder and borderline personality disorder, since many seem to act as mood stabilizers, and for the treatment of neuropathic pain. Anticonvulsants suppress the excessive rapid firing of neurons during seizures. Anticonvulsants also prevent the spread of the seizure within the brain.Conventional antiepileptic drugs may block sodium channels or enhance γ-aminobutyric acid (GABA) function. Several antiepileptic drugs have multiple or uncertain mechanisms of action. Next to the voltage-gated sodium channels and components of the GABA system, their targets include GABAA receptors, the GAT-1 GABA transporter, and GABA transaminase. Additional targets include voltage-gated calcium channels, SV2A, and α2δ. By blocking sodium or calcium channels, antiepileptic drugs reduce the release of excitatory glutamate, whose release is considered to be elevated in epilepsy, but also that of GABA. This is probably a side effect or even the actual mechanism of action for some antiepileptic drugs, since GABA can itself, directly or indirectly, act proconvulsively. Another potential target of antiepileptic drugs is the peroxisome proliferator-activated receptor alpha. The drug class was the 5th-best-selling in the US in 2007.Some anticonvulsants have shown antiepileptogenic effects in animal models of epilepsy. That is, they either prevent the development of epilepsy or can halt or reverse the progression of epilepsy. However, no drug has been shown in human trials to prevent epileptogenesis (the development of epilepsy in an individual at risk, such as after a head injury)..
What does the word anticonvulsant mean? Find synonyms, antonyms and the meaning of the word anticonvulsant in our free online dictionary! Find words starting with anticonvulsant and anagrams of anticonvulsant.
Definitions of "anticonvulsant"
- A drug that prevents or relieves convulsions. noun
- An agent that prevents, stops, or lessens convulsions. noun
- Acting as an anticonvulsant. adjective
- a drug used to treat or prevent convulsions (as in epilepsy) noun
The word "anticonvulsant" in example sentences
The bag contained Keppra, an anticonvulsant that sometimes alleviates headaches.. [Chocolate & Vicodin]
It was amazing how one simple thing, a headache, could cause a chain reaction in my life that eventually led to me sitting on my couch, watching anticonvulsant medication drip into my veins, while a strange woman did paperwork at my kitchen counter.. [Chocolate & Vicodin]
Vivus of Mountain View, CA is testing a combination of low doses of the active ingredients phentermine and topiramate (an anticonvulsant) under the name Qnexa.. [SciFi, Fantasy & Horror Collectibles - Part 1066]
Flumazenil must be used with caution in patients who have been on benzodiazepines for long-term sedation, anticonvulsant therapy, or in overdose cases where cyclic antidepressants or other seizurogenic drugs were ingested.. [Flumanazil]
CBZ follows first-order, nonsaturable kinetics. 1,2 CBZ is metabolized in the liver to several metabolites, the primary metabolite being CBZ-10,11 epoxide (CBZ-E) .1,2 CBZ-E possesses anticonvulsant activity similar to the parent drug.. [Carbamazepine]
The inhibitory effect of the GABA/benzodiazepine complex on neuronal discharge produces sedation, anticonvulsant activity, anxiolysis and striated muscle relaxation. 6,7,8,9. [Flumanazil]
These alternative anticonvulsant drugs AACDs include felbamate, gabapentin, levetiracetam, pregabalin, topiramate and zonisamide.. [Dr. Karen Becker: Treating Seizure Disorders in Pets]
Because of the problems associated with traditional seizure medications, other types of human anticonvulsant drugs have been tested for use in veterinary medicine.. [Dr. Karen Becker: Treating Seizure Disorders in Pets]
Although bromides are considered safer drugs than phenobarbital, they may not completely control seizures as a sole medication and are most commonly used in conjunction with other anticonvulsant drugs.. [Dr. Karen Becker: Treating Seizure Disorders in Pets]
• Phenytoin, an anticonvulsant that has been used to treat epilepsy. [Monday Midday « Gerry Canavan]
Seizures can be managed with conventional anticonvulsant therapy.. [Monamine Oxidase Inhibitors]
These include two beta-blockers that are also used to treat high blood pressure — propranolol (Inderal and generic) and timolol — and two anticonvulsant drugs, topiramate (Topamax and generic) and valproic acid (Depakote and generic).. [Botox added to arsenal of treatment options for chronic migraines]
Qnexa is a combination of two older drugs: the amphetamine phentermine and topiramate, an anticonvulsant drug sold by Johnson & Johnson as Topamax.. [FDA To Review First Of 3 New Weight Loss Drugs]
Two of the drugs submitted for approval simply combine existing drugs – an anticonvulsant and an amphetamine – but have worrying side effects.. [FDA To Review First Of 3 New Weight Loss Drugs]
If you or somebody you care for takes the anticonvulsant drug lamotrigine (Lamictal and generic), you should be aware that in rare cases it can cause inflammation of the membranes that cover the brain and spinal cord, a serious condition known as aseptic meningitis.. [Epilepsy, bipolar drug Lamictal linked to brain inflammation]
She swallows her doses of anticonvulsant; she cranks in laundry from the lines in the garden.. [Memory Wall]
Anticonvulsant TranslatesAnticonvulsant English to Turkish Translate
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