Antimetabolites

• Receiving antimetabolites or chemotherapeutic agents ❋ Bridget Swinney (2007)

Hitchings studied how false building blocks, the so-called antimetabolites, could be used to interrupt cellular growth. ❋ Unknown (1988)

This convinced us, as well as many other investigators in the cancer field, that antimetabolites of nucleic acid bases were fruitful leads to follow. ❋ Unknown (1988)

In the early days of seeking antimetabolites for the natural purines in our laboratory, xanthine oxidase had been one of test enzymes. ❋ Unknown (1988)

Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids used in greater than physiologic doses, may reduce the immune responses to vaccines ❋ Unknown (2010)

The antimetabolites are forecast to account for the largest proportion of market share through to 2018 14 ❋ Unknown (2009)

Immunosuppressive therapies, including irradiation, antimetabolites, alkylating agents, cytotoxic drugs, and corticosteroids (used in greater than physiologic doses), may reduce the immune responses to vaccines

The mechanism of action of antimetabolites is through the inhibition of nucleotide and nucleic acid synthesis. ❋ Unknown (2009)

Chemotherapeutics [antimetabolites, nucleoside analogues topoisomerase inhibitors, and HDAC inhibitors] ❋ Unknown (2009)

Immunosuppressive therapies including irradiation, antimetabolites, alkylating agents, cytotoxic drugs and corticosteroids (used in greater than physiologic doses), may reduce the immune response to vaccines. ❋ Unknown (2008)

"Some of the antimetabolites and other cellular poisons. ❋ Cook, Robin, 1940- (2000)

The purpose was twofold, to characterize the metabolic pathways involved in the biosynthesis of nucleic acids and to identify antimetabolites in the nucleic acid metabolism (Figure ❋ Unknown (1988)