Antisense

Word ANTISENSE
Character 9
Hyphenation N/A
Pronunciations /ˌæntaɪˈsɛns/

Definitions and meanings of "Antisense"

What do we mean by antisense?

Of or relating to a nucleotide sequence that is complementary to a sequence of messenger RNA. When antisense DNA or RNA is added to a cell, it binds to a specific messenger RNA molecule and inactivates it. adjective

A molecule which interacts with a complementary strand of nucleic acids, so as to suppress its transcription. noun

A molecule which interacts with a complementary strand of nucleic acids, so as to suppress its transcription.

Synonyms and Antonyms for Antisense

  • Synonyms for antisense
  • Antisense synonyms not found!!!
  • Antonyms for antisense
  • Antisense antonyms not found!

The word "antisense" in example sentences

The researchers also suppressed CPE-delta N in mice using an experimental approach called antisense and found tumors implanted into the animals did not spread. ❋ Unknown (2011)

Simard's team blocked this gene in mice and rats using gene-blocking therapy called antisense and showed that after a spinal cord injury, the damage and effects were much less without ABCC8. [email protected] (2010)

Researchers demonstrate efficacy of antisense therapy for spinal muscular atrophy disease spinal muscular atrophy (SMA) might soon be treated with tiny, chemically modified pieces of RNA called antisense oligonucleotides (ASOs). ❋ Unknown (2010)

Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists conducted studies in which nine rhesus monkeys were challenged with lethal Ebola virus, reports ❋ Unknown (2010)

In the study, Simard and his colleagues gave a drug called antisense oligodeoxynucleotide ❋ Unknown (2010)

Isis Pharmaceuticals, Inc. engages in the discovery and development of a new class of drugs called antisense drugs using antisense technology, a novel drug discovery platform to generate ❋ Unknown (2010)

Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists first performed a series of studies with mouse and guinea pig models of Ebola to screen various chemical variations. ❋ Unknown (2010)

If a gene is read forwards - called 'sense' transcription - the protein is generated in the normal way, but if the other, complementary strand is transcribed - called antisense - no protein is made. ❋ Unknown (2009)

"Exon-skipping" employs synthetic DNA-like molecules called antisense as a DNA band-aid to skip over the parts of the gene that block the effective creation of dystrophin. ❋ Unknown (2009)

In the early 1990s, Gilead believed that it could develop a new class of drugs, called antisense, that would block harmful genes from doing mischief. ❋ Unknown (2009)

The study, which is published in the journal Molecular Cell, demonstrates that Wrap53 gives rise to a molecule, called antisense RNA, the presence of which is necessary for the production of sufficient quantities of p53 protein in the event of DNA damage.

Unlike traditional gene therapy, which attempts to replace a mutated gene with a functional copy, exon skipping relies on a variation of a technique called antisense, in which short synthetic DNA or RNA molecules are designed to bind to a region of DNA or RNA and block its function. ❋ Unknown (2009)

DIG-labelled antisense RNA probes synthesis, samples fixation and in situ hybridisation were carried out as previously described ❋ Unknown (2009)

Cross Reference for Antisense

  • Antisense cross reference not found!

What does antisense mean?

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