Antithymocyte

Patients received a conditioning regimen that consisted of total body irradiation (1375 cGy in 11 fractions) with partial lung shielding, thiotepa (10 mg/kg), cyclophosphamide (120 mg/kg), and rabbit antithymocyte globulin (1.5 mg/kg).

The data presented showed that patients treated with ABX-CBL, an anti-CD147 monoclonal antibody, were similar to the control arm [antithymocyte globulin]. ❋ Unknown (2009)

Demonstrate superior survival rate at 180 days compared to antithymocyte globulin [ATG], the study's control arm ❋ Unknown (2009)

In our recently reported prospective, randomized, international clinical trial comparing rabbit antithymocyte globulin and basiliximab in renal transplantation (ClinicalTrials. gov number, NCT00235300 [ClinicalTrials. gov]) ,1 we observed that induction treatment with rabbit antithymocyte globulin was as safe as and more effective than basiliximab at 1 year in preventing acute rejection in patients who had received kidney transplants from deceased donors and who were at increased risk for acute rejection or delayed graft function. ❋ Unknown (2008)

Whether the apparent benefits of rabbit antithymocyte globulin over basiliximab persist is unknown. ❋ Unknown (2008)