Several hints pointed out in the late 1990s to a possible role for anti-apoptotic molecules such as bcl-2 (60), soluble Fas (61-63) and active NF-κB (64-66). ❋ Unknown (2009)
In post 12, bcl says: “Seems pretty close to slander to me.” ❋ Unknown (2007)
Posted Aug 15, 2007 at 12:57 PM | Permalink | Reply bcl ❋ Unknown (2007)
Posted Jun 19, 2007 at 7:24 AM | Permalink | Reply bcl ❋ Unknown (2007)
Posted Aug 15, 2007 at 7:52 AM | Permalink | Reply bcl ❋ Unknown (2007)
To evaluate whether down-regulation of bcl-2 shows opposite effect of bcl-2 overexpression in terms of HIF-1α protein expression, we silenced the endogenous expression of bcl-2 gene transfecting M14 cells with siRNA-targeting bcl-2 mRNA (si-bcl-2) and then exposing them to normoxia or hypoxia for 24 h. ❋ Daniela Trisciuoglio Et Al. (2010)
Moreover, the treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide exterts antiangiogenic activity ❋ Daniela Trisciuoglio Et Al. (2010)
(IP) with anti-HSP90 or control (IgG) antibodies and then the Western blot analysis was performed using anti-HIF-1α, anti-bcl-2 and anti-HSP90 antibodies. ❋ Daniela Trisciuoglio Et Al. (2010)
Giorgini S, Trisciuoglio D, Gabellini C, Desideri M, Castellini L, et al. (2007) Modulation of bcl-xL in tumor cells regulates angiogenesis through CXCL8 expression. ❋ Daniela Trisciuoglio Et Al. (2010)
Whole cell lysates were sequentially immunoprecipitated with anti-HIF-1α (IP1) and anti-bcl-2 antibodies (IP2) and then the Western blot analysis was performed using anti-HSP90 antibody. ❋ Daniela Trisciuoglio Et Al. (2010)
Whole cell lysates were immunoprecipitated (IP) with anti-bcl-2 or control (IgG) antibodies and then the Western blot analysis was performed using anti-HIF-1α and anti-bcl-2 antibodies. ❋ Daniela Trisciuoglio Et Al. (2010)
To address this hypothesis, the cell lysates were firstly immunoprecipitated with anti-HIF-1α antibody, then subjected to a second immunoprecipitation with anti-bcl-2 antibody, and the immunocomplexes were analyzed by Western blot analysis using antibody against HSP90 protein. ❋ Daniela Trisciuoglio Et Al. (2010)
Pazyra-Murphy MF, Hans A, Courchesne SL, Karch C, Cosker KE, et al. (2009) A retrograde neuronal survival response: target-derived neurotrophins regulate MEF2D and bcl-w. ❋ Hortensia Sanchez-Calderon Et Al. (2010)
(A) Western blot analysis of HIF-1α and bcl-2 protein expression in total extracts of M14 cells transfected with siRNA targeting bcl-2 mRNA (si-bcl-2) or with a control scrambled si-RNA (si-contr) and then exposed to normoxia or hypoxia for 24 h. ❋ Daniela Trisciuoglio Et Al. (2010)
(IgG) and then the Western blot analysis was performed using anti-bcl-2 or anti-HIF-1α antibodies. ❋ Daniela Trisciuoglio Et Al. (2010)
Nuclear (Nucl) and cytoplasmic (Cyto) protein extracts were immunoprecipitated (IP) with anti-HIF-1α or anti-bcl-2, respectively, or control antibody ❋ Daniela Trisciuoglio Et Al. (2010)
McIntosh BC, Greenberg PD, Nelson BH (2000) The IL-2 receptor promotes lymphocyte proliferation and induction of the c-myc, bcl-2, and bcl-x genes through the trans-activation domain of Stat5. ❋ Yo-Ping Lai Et Al. (2009)
Cells were selected either by culture in the presence of 2 µg/ml puromycin (LMP-msiGR) or 200 mg/ml neomycin (pEYZ/MCS-bcl-2). ❋ Simone Wüst Et Al. (2009)
Gonzalez-Garcia M, Postema CE, Ding L, Lindsten T, et al. (1993) bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. ❋ Unknown (2008)
MARC Classification Sources Addition:bcl - Nederlandse Basisclassificatie = Dutch Basic ❋ David Bigwood (2005)
[dude], there [goes] the [bcl's]. ❋ Heatha (2004)
"Where are you [gunna] pick up beer for tonight?"
"the [BCL] [on main]" ❋ Bougiegurl (2011)
[Everytime] I [wear] my [jocks], I get BCL. ❋ Bread Infection (2005)
His BCL was [delicious]. ❋ Ling Ho (2008)
Blake is such a BCL Baller! Yeah, he should be [strutting] [his asshole] out on [Dancing with the Stars]. ❋ Lovell From UT (2010)
Steig and Art are in the [conference room] talking about how to run the streaming [software company] into the ground, planning how to backstab their co-workers, and how overthrow the founder(s) of the company.
As Mark would say... "they're doin the [BCL]" ❋ Crazy Pedro (2005)
yo, [i saw] [that girl] you [told] me about, she was bad like bcl-2 bro. ❋ Twelve Express (2020)
You [seem] to be [acting BCL] [right now] ❋ Are You Tired Of The Adds (2023)