Cannabinoid

Figure 5.2 Avoiding the Issue We call the cannabinoid system the “can’t avoid” system because when it’s activated, the fact is, it’s awfully hard to avoid the foods you should. ❋ Michael F. Roizen (2008)

There are these receptors in the brain called cannabinoid receptors. ❋ Unknown (2009)

THC acts upon specific sites in the brain, called cannabinoid receptors, kicking off a series of cellular reactions that ultimately lead to the "high" that users experience when they smoke marijuana. ❋ Unknown (2009)

The drugs, known as cannabinoid-receptor, or CB-1, antagonists, are designed to block certain brain receptors that regulate appetite. ❋ Unknown (2008)

This actually blocks what is known as the cannabinoid receptors in the brain. ❋ Unknown (2008)

When one of our systems, called the cannabinoid system described on page 161, is turned on, hormones in the body block the ability of insulin to get muscle to use sugar, and we accumulate sugar in our bloodstream as our metabolism actually becomes less efficient. ❋ MEHMET C. OZ (2007)

PEEKE: And the pill actually is called a cannabinoid (ph) one receptor blocker for crying out loud. ❋ Unknown (2006)

In studies, drugs have been developed to block a receptor in the brain that is activated by cannabis compounds called the cannabinoid CB1 receptor in the hope that the drugs would reduce hunger. ❋ Unknown (2011)

THC finds brain cells, or neurons, with specific kinds of receptors called cannabinoid receptors, to which it binds.

THC is the main active ingredient in marijuana because it affects the brain by binding to and activating specific receptors, known as cannabinoid receptors. ❋ Unknown (2009)

It does as much harm as any other endogenous cannabinoid, which is none. ❋ Unknown (2009)

They said the spray works by activating molecules in the body called cannabinoid receptors which can stop nerve signals being sent to the brain from the site of pain. ❋ Unknown (2009)

The three scratched drugs belong to a group called cannabinoid receptor antagonists. ❋ Unknown (2008)

Other promising drugs work through a biological pathway called the cannabinoid system, which we’ll discuss in chapter 8. ❋ MEHMET C. OZ (2007)

They also found that the compound did not affect behavioral responses, such as cannabinoid-induced immobility and hypothermia, that are mediated by endocannabinoid receptors in the brain, and that it reduced weight in mice with diet-induced obesity by about 12 percent, but did not affect weight in mice with a genetic predisposition for obesity. ❋ Unknown (2010)

❋ Root (2003)

Those [cannabinoids] [sure] make [the day] better. ❋ PineappleJuice (2015)

[Laurel]: Are you in Anthropology 102? Kevin: Yea, we are learning about hominoids. Laurel: *[hits blunt]* i'm stoned dude, I feel like a [cannabinoid]... Kevin: ...The highest of the high...*Laurel passes kevin the blunt* Kevin: *hits blunt* ❋ Kevinlaurel420 (2015)

"Hey, where you high when you [wrote] this? Cause this [message] sounds [cannabinoidely optimistic]. " ❋ UrpalKate (2009)

Steve: [Smoke weed everyday]! *Smokes weed Andre: I'm not sure you should smoke that stuff everyday. No one knows the long term effects. I only chug [Kratom] twice a week. *[chugs] Kratom (several years later) Steve: *vomits brahdhrb *Smokes weed Smoke weed everyday. Andre: I found out about something called cannabinoid hyperemesis syndrome. I think you might have it. Or maybe it's cyclical vomiting. *chugs Kratom Doctor: Steve! You have cannabinoid hyperemesis syndrome. I thought it was cyclical vomiting but you tested positive for THC and have a history of smoking marijuana everyday. You have to quit cannabis, or weed. You can never smoke weed again! You should have used moderation. Steve: Nooooooo! Steve: *Quits weed for 3 months Steve: Hey! The nausea is gone. Andre: Cool! Wanna chug Kratom? Steve: Sure! *chugs Kratom Andre: *chugs Kratom Tyler: I only smoke weed when going on a boat fishing. It helps with nausea. Other times, it's [kratom]. *Smokes weed. *chugs kratom. ❋ CognitiveFuel (2023)

"Substances like THC, CBD, CBN, [THCV], Delta-8-THC, HHC, H4CBD, THCP, HHCP, HU-210, HU-243, AM-905, AM-087, AM-411, belong to the classical [cannabinoid] structural class." "[Classical cannabinoids] aren't like the cannabinoids that went into spice/k2 smoke blends which belong to a completely different structural class." "JWH-091 (D8-THCP) belongs to the classical cannabinoid structural class but JWH-018 belongs to the alkyl-naphthoylindole structural class, despite both being cannabinoid agonists, and the JWH nickname, they are structurally unrelated to eachother." "Classical cannabinoids were the first structural class of cannabinoids to ever be discovered." ❋ ClassicalCannabinoids (2023)