Secondly, the length of feeding was at most only three months, and thus only relatively acute and medium-term effects can be observed if any similar to what can be derived in a process such as carcinogenesis [ ❋ Unknown (2010)
We can do autopsies on persons who smoked, we can do toxicologic studies on their lungs, we can perform carcinogenesis studies on chemicals in cigarette smoke, and we can gather epidemiologic data on smoking and diseases such as emphysema, lung cancer, and heart disease. ❋ Unknown (2009)
The early hypothesis that cervical cancer was caused by papillomaviruses, the successful isolation and characterisation of the two most frequent HPV types in this cancer and the subsequent steps leading to a better understanding of the mechanism of HPV-mediated carcinogenesis and eventually to the development of a preventive vaccine were cited as the prime reasons for awarding one half of the Nobel Prize for Medicine or Physiology to me in 2008. ❋ Unknown (2009)
Despite an apparent lack of studies comparing the effects of fermented vs. nonfermented soy foods on tumor development in lab animals, studies of miso show that it inhibits breast, stomach and colon carcinogenesis. ❋ Craig Cooper (2010)
The long, slow march of carcinogenesis—the methodical, step-by-step progression of early-stage lesions of cancer into frankly malignant cells—inspired another strategy to prevent cancer. ❋ Siddhartha Mukherjee (2010)
Chemoprevention of N-nitroso-N-methylurea-induced rat mammary carcinogenesis by soy foods or biochanin A. ❋ Craig Cooper (2010)
By the late 1970s, the theory of carcinogenesis proposed by Varmus and Bishop had also generated at least one such risky prediction. ❋ Siddhartha Mukherjee (2010)
His discovery of reverse transcription had certainly overturned the dogma of cellular biology, but it had not pushed the understanding of human carcinogenesis far. ❋ Siddhartha Mukherjee (2010)
A rather general conceptual framework for carcinogenesis was slowly becoming apparent. ❋ Siddhartha Mukherjee (2010)
But the set of disparate observations—from Blumberg to Ames to Warren and Marshall—could not simply be stitched together into a coherent theory of carcinogenesis. ❋ Siddhartha Mukherjee (2010)
The committee was split exactly five to five among nonsmokers and smokers—men whose addiction was so deep that it could not be shaken even when deliberating the carcinogenesis of smoke. ❋ Siddhartha Mukherjee (2010)
Could one thwart the march of carcinogenesis in midstep? ❋ Siddhartha Mukherjee (2010)
Activating or inactivating any single gene, he postulated, produced only the first steps toward carcinogenesis. ❋ Siddhartha Mukherjee (2010)
He discovered the genetic basis for the process by which normal cells are transformed into cancer cells, known as chemical carcinogenesis, a discovery that was considered a major advance in the field. ❋ Unknown (2010)
Louis Fieser, an organic chemist from Harvard, was an expert on chemical carcinogenesis. ❋ Siddhartha Mukherjee (2010)
One afternoon, I watched Tom Lynch, the lung cancer clinician, masterfully encapsulate carcinogenesis, cancer genetics, and chemotherapy for a new patient, a middle-aged woman with bronchoalveolar cell cancer. ❋ Siddhartha Mukherjee (2010)
Dr. Gelboin was chief of the molecular carcinogenesis laboratory at the National Cancer Institute from 1966 to 1999. ❋ Unknown (2010)
New insights into carcinogenesis, and new therapeutic inroads would instantly follow. ❋ Siddhartha Mukherjee (2010)
