For instance, targeting of genes encoding components of the contractile apparatus in cardiomyocytes leads to cardiomyopathy; targeted mutations in connexin proteins of gap junctions cause conduction defects; disrupted genes for transcription factors involved in heart development lead to congenital heart malformations; and targeting of genes controlling energy metabolism causes cardiomyopathy. ❋ Unknown (2007)
"Everyone started putting bone marrow in the heart," says Christine Mummery, a researcher at Leiden University Medical Center in the Netherlands, who has studied how to turn stem cells into heart muscle cells called cardiomyocytes. ❋ Unknown (2011)
After these conditions damage the heart, heart muscle cells called cardiomyocytes enlarge as the body tries to respond and compensate, increasing the organ's size. ❋ Unknown (2010)
Earlier research by Yeh and colleagues showed CD34+ cells are capable of becoming heart muscle cells, called cardiomyocytes, blood vessel cells and smooth muscle cells. ❋ Unknown (2010)
Instead, repair is accomplished by differentiated cardiac muscle cells known as cardiomyocytes, those cellular grown-ups whose normal job is to supply the contractile force of the heart. ❋ PhysOrg Team (2010)
The main problem is that when beating muscles cells - known as cardiomyocytes - die during an attack there is no way to reactivate them and the surrounding ❋ Unknown (2010)
This remarkable heart repair is achieved by differentiated cardiac muscle cells called cardiomyocytes -- not stem cells, but mature cells that normally supply the contractile force of the heart. ❋ Unknown (2010)
The main problem is that when beating muscles cells - known as cardiomyocytes - die during an attack there is no way to reactivate them and the surrounding connective tissue - known as fibroblasts - cannot take over their role. ❋ Unknown (2010)
We know that heart muscle cells, also known as cardiomyocytes, proliferate when the baby is still in the womb. ❋ Unknown (2009)
But recent studies have shown that these heart muscle cells, known as cardiomyocytes, do have a limited ability to replace themselves. ❋ Unknown (2009)
Heart muscle cells, also known as cardiomyocytes, do proliferate during prenatal development. ❋ Unknown (2009)
In particular, he noted that the study authors failed to show creation of cells called cardiomyocytes, which cause heart muscle to beat. ❋ Unknown (2008)
5,043 U.S. patents issued yesterday, covers a process of creating the cells -- known as cardiomyocytes.
Because iPSCs have been shown to behave similarly to embryonic stem cells with the ability to differentiate into various cell types, such as cardiomyocytes, hepatocytes, neurons and pancreatic cells, and can be created from any adult somatic cell, like a skin cell, iPSC technology has significant commercial and medical value. ❋ Pillscribe (2010)
Over time, they begin to specialize as specific cell types, such as cardiomyocytes of the heart or neurons of the brain. ❋ Unknown (2010)
