I would like to digress at this point, to describe another use for allopruinol which materialized about 10 years later, because it typifies the kind of chemotherapeutic selectivity which can be achieved with purine analogs as the result of differences in the specificties of parasitic and mammalian enzymes. ❋ Unknown (1988)
Future work must delineate the social and biological factors, including any differences in pharmacokinetics associated with chemotherapeutic agents, that account for disparities in outcome. ❋ Unknown (2010)
She could not choose the chemotherapeutic agents he would be given or order the blood tests that frequently needed to be sent. ❋ Md Meghan Maclean Weir (2011)
You know, most chemotherapeutic agents cause hair loss and nausea, and you get very sick and debilitated because not only are they killing the cancer cells, but they're also killing the healthy cells. ❋ Unknown (2010)
Drugs used include cidofovir, interferon alpha and other experimental chemotherapeutic regimens. ❋ Unknown (2010)
After all, aspirin was originally derived from willow bark, and the anticancer chemotherapeutic agent Taxol was derived from the bark of the Pacific yew tree. ❋ Donna Jackson Nakazawa (2008)
A chemotherapeutic poison was a poison was a poison, and one did not need to understand a cancer cell to poison it. ❋ Siddhartha Mukherjee (2010)
Others contended that the chemotherapeutic battle against cancer needed to be taken to the brink. ❋ Siddhartha Mukherjee (2010)
VAMP had succeeded, Frei privately believed, not just because of the unique chemotherapeutic synergy among the drugs, but also because of the unique human synergy at the NCI—that cocktail of brilliant young minds and risk-taking bodies that had coalesced in Bethesda between 1955 and 1960. ❋ Siddhartha Mukherjee (2010)
But for a vast majority of cancers, more intensive regimens of standard chemotherapeutic drugs did not necessarily mean more survival. ❋ Siddhartha Mukherjee (2010)
Her doctors in Alabama cobbled together a combination of chemotherapeutic drugs, but they were essentially biding their time. ❋ Siddhartha Mukherjee (2010)
The FDA said the "risk-benefit ratio of [Avastin] when added to the standard chemotherapeutic regimens ... may not be considered favorable." ❋ Unknown (2010)
Unfortunately, metastatic melanoma is extremely aggressive and very resistant to existing chemotherapeutic regimens. ❋ M.D. Nicholas Perricone (2010)
A “large-scale chemotherapeutic attack,” as one doctor put it, was needed to obliterate cancer. ❋ Siddhartha Mukherjee (2010)
Unlike Frei, though, Canellos had turned from advocate to adversary of megadose chemo regimens, in part because he had been among the first to notice a devastating long-term side effect: as doses escalated, some chemotherapeutic drugs damaged the marrow so severely that, in time, these regimens could precipitate a premalignant syndrome called myelodysplasia, a condition that tended to progress to leukemia. ❋ Siddhartha Mukherjee (2010)
I suggested that we try a palliative drug, perhaps a single chemotherapeutic agent that might just ameliorate her symptoms rather than pushing for a tougher regimen to try to cure an incurable disease. ❋ Siddhartha Mukherjee (2010)