Coxsackievirus

In 1996, WHO responded to an outbreak of aseptic meningitis in Cyprus caused by a non-polio enterovirus identified as coxsackievirus B5. ❋ Unknown (1998)

When coxsackievirus B3 first enters the immune system, it enters the mast cells, where it gets broken down and chopped up. ❋ Donna Jackson Nakazawa (2008)

Meanwhile, unbeknown to her, her two-year-old is coming down with a coxsackievirus she picked up at daycare, and Mom just shared the end of a Popsicle with her, so the virus is beginning to work on her mast cells as well. ❋ Donna Jackson Nakazawa (2008)

To see how this process occurs in real time, Fairweather works in her lab with mice that have been exposed to a common virus such as coxsackievirus B3, known for short as CVB3, which can cause low-grade abdominal distress and diarrhea. ❋ Donna Jackson Nakazawa (2008)

The immune system must now decide whether to fight the coxsackievirus B3. ❋ Donna Jackson Nakazawa (2008)

"Treatment of viral myocarditis caused by coxsackievirus" B. ❋ Unknown (2010)

Dr. Didier Hober, a professor of virology at University Lille in France and author of an accompanying journal editorial, said "the increased incidence rate of type 1 diabetes can be explained by a role of environmental factors, especially enteroviruses, like coxsackievirus B." ❋ Unknown (2011)

The cells are resistant, however, to adenovirus 5, coxsackievirus B5, and poliovirus 2.

PtK2 cells are susceptible to coxsackievirus A9, herpes simplex, vaccinia, and vesicular stomatitis (Ogden strain).

The cells exhibit resistance to coxsackievirus B3 and B4 as well as poliovirus 2, and are negative for reverse transcriptase.

Viruses that MDCK cells are susceptible to include vesicular stomatitis (Indiana strain), vaccinia, coxsackievirus B5, reovirus 2 and 3, adenovirus 4 and 5, vesicular exanthema of swine, and infectious canine hepatitis.

The cells, which appear to senesce after approximately 40 passages, are susceptible to herpes simplex, reovirus 3, vesicular stomatitis (Ogden strain), and vaccinia, but resist adenovirus 5, coxsackievirus A9 and B5, and poliovirus 2.