A medicine called diclofenac, which is used to treat livestock and is consumed by vultures while feeding on animals 'carcasses, is believed to be the main cause of vulture deaths and therefore the decline in its population. ❋ Unknown (2010)
Wolfe pointed out that trial data presented by Merck on cardiovascular risks compared etoricoxib with diclofenac, which is much more cardio-toxic than older, safer pain relievers. ❋ Unknown (2007)
She added that an increased risk of stroke was also found for veterans taking the commonly used NSAID diclofenac, which is available without a prescription. ❋ Unknown (2011)
NSAID called diclofenac with a medication to prevent ulcers called misoprostol. ❋ Unknown (2011)
One example is diclofenac, which is available in a few different forms: as a gel (Voltaren) ❋ Unknown (2010)
An anti-inflammatory drug for cattle, called diclofenac, has been blamed for poisoning the birds, which eat the carcasses of the dead livestock. ❋ Unknown (2008)
But since surveys began in the 1990s, their numbers have sunk by 99.9 percent, in part from ingesting a deadly anti-inflammatory drug, called diclofenac, found in dead livestock. ❋ Unknown (2008)
At first the cause was unclear, but researchers eventually zeroed in on an anti-inflammatory drug, diclofenac, that is used to alleviate arthritis-like symptoms in livestock but is toxic to vultures. ❋ Unknown (2008)
A 2006 analysis of 138 randomized trials and almost 150 000 participants showed that selective COX-2 inhibitors are associated with a moderately increased risk of vascular events, mainly due to a twofold increased risk of myocardial infarction, that is heart attacks, and also that high-dose regimens of some traditional NSAIDs such as diclofenac and ibuprofen are associated with a similar increase in risk of vascular events. ❋ Dr. Andrew Lange (2010)
University of Bern in Switzerland, said: The use of other non-steroidal anti-inflammatory drugs not covered by our analysis should be reconsidered, as well as the over the counter availability of non-steroidal anti-inflammatory drugs such as diclofenac or ibuprofen. ❋ Unknown (2011)
Preventing the misuse of human diclofenac for veterinary use remains the main challenge in halting the decline of endangered vultures. ❋ Unknown (2011)
With the latest success of the breeding centres we're more confident than ever that there will be sufficient numbers for reintroduction to the wild as soon as it's safe for them, but until diclofenac stops being produced and sold for veterinary use we cannot guarantee these birds have any future in the wild. ❋ Unknown (2011)
Highest risk of miscarriage was associated with diclofenac and lowest risk with rofecoxib. ❋ Ann Lukits (2011)
A newly published study in PLOS Medicine linked diclofenac to an increased risk of heart attack and stroke. ❋ Ann Lukits (2011)
Naproxen (Aleve, Naprosyn, and generic) appeared to pose the lowest risk of a heart attack, while diclofenac (Voltaren and generic) had the highest risk of cardiovascular death among the NSAIDs currently available in the U.S. ❋ Unknown (2011)
Diclofenac almost tripled the risk, while etoricoxib and diclofenac were associated with around a fourfold increased risk of suffering death from cardiovascular causes. ❋ Unknown (2011)
Some of the diclofenac on sale is formulated for veterinary use and has been manufactured illegally since the ban was brought in by India, Pakistan and Nepal, the research published in the journal Oryx found PDF. ❋ Unknown (2011)
A study led by the RSPB's principal conservation scientist, Richard Cuthbert, found more than one-third of Indian pharmacies are still selling diclofenac, a non-steroid anti-inflammatory drug, which can be used in humans as well as by farmers treating cattle. ❋ Unknown (2011)
The drug diclofenac was banned because it led to population crashes in three species of vulture in south Asia with birds dying of kidney failure after feeding on carcasses of cattle treated with the medication. ❋ Unknown (2011)
