Disulfiram Wiki - What is the disulfiram?
Disulfiram (sold under the trade names Antabuse and Antabus) is a drug used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme acetaldehyde dehydrogenase, which means that many of the effects of a "hangover" are felt immediately after alcohol is consumed. "Disulfiram plus alcohol, even small amounts, produce flushing, throbbing in head and neck, throbbing headache, respiratory difficulty, nausea, copious vomiting, sweating, thirst, chest pain, palpitation, dyspnea, hyperventilation, tachycardia, hypotension, syncope, marked uneasiness, weakness, vertigo, blurred vision, and confusion. In severe reactions there may be respiratory depression, cardiovascular collapse, arrhythmias, myocardial infarction, acute congestive heart failure, unconsciousness, convulsions, and death."In the body, alcohol is converted to acetaldehyde, which is then broken down by acetaldehyde dehydrogenase. If the dehydrogenase enzyme is inhibited, acetaldehyde builds up and causes unpleasant effects. Disulfiram should be used in conjunction with counseling and support. Disulfiram has been studied as a possible treatment for cancer and latent HIV infection. .
What does the word disulfiram mean? Find synonyms, antonyms and the meaning of the word disulfiram in our free online dictionary! Find words starting with disulfiram and anagrams of disulfiram.
Definitions of "disulfiram"
- A drug used in the treatment of alcoholism that interferes with the metabolic degradation of alcohol, producing an unpleasant reaction when even a small quantity of alcohol is consumed. noun
- A drug, 1-(diethylthiocarbamoyldisulfanyl)- N,N-diethyl-methanethioamide, used to treat chronic alcoholism noun
- a drug (trade name Antabuse) used in the treatment of alcoholism; causes nausea and vomiting if alcohol is ingested noun
The word "disulfiram" in example sentences
It's based on as-yet-unpublished laboratory experiments about the effect of Antabuse, also known as disulfiram, on latent HIV by Robert Siliciano, a professor of medicine at Johns Hopkins in Baltimore.. [BusinessWeek.com -- Top News]
If patient is being treated for alcohol deaddiction with a drug called disulfiram. [Yahoo! Answers: Latest Questions]
It's a strong deterrent to drinking, much like the drug disulfiram, or Antabuse.. [In Search of Alcoholism Genes]
There are already several drugs approved in Europe and the U.S. to treat alcoholism, including disulfiram, which discourages drinking by causing unpleasant effects when even small amounts of alcohol are consumed.. [Danish Alcoholism Drug Does Well in Three Clinical Trials]
The oldest and best-known is disulfiram, or Antabuse, which makes people vomit as soon as they drink but doesn't reduce cravings.. [New Hope For Addicts?]
One of those that acts as a deterrent, for example, is disulfiram Antabuse, which is used in the treatment of alcohol dependence.. [Helping the Addict You Love]
As I explained in chapter 9, medications like naltrexone and disulfiram can be used effectively to both help your friend or loved one stop abusing a substance and to help him or her after he or she has stopped.. [Helping the Addict You Love]
The clinician should take measures e.g., ask a friend or relative to dispose of any weapons, arrange for outpatient follow-up, give the patient appropriate medication, provide for treatment in the event of an emergency, give disulfiram if the patient is alcoholic to decrease the probability of violence.. [The Neuropsychiatric Guide to Modern Everyday Psychiatry]
Although millions of doses of disulfiram Antabuse have been prescribed for the treatment of alcoholism since 1938, well-controlled studies have never demonstrated that it is more effective than a placebo in producing sustained abstinence….. [Alcohol and The Addictive Brain]
Brand name for disulfiram, an antioxidant used in aversion therapy to create an aversion to alcohol.. [Alcohol and The Addictive Brain]
People should talk with their doctor if they take or plan to take metronidazole (Flagyl®) or disulfiram (Antabuse®).. [WebWire | Recent Headlines]
People should talk with their doctor if they are taking or planning to take Flagyl® (metronidazole) or Antabuse® (disulfiram).. [BioSpace.com Featured News and Stories]
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