She has double-cone specials today – any 2 specials, a lot of them available, on a double cone for $5 during lunch. ❋ Unknown (2009)
- Point angle 80° - 90° (1) or double-cone drill point (2) ❋ Unknown (1990)
Vesuvius is a familiar example of simple complication, the double-cone volcano, while Mauna Loa in Hawaii, including Kilauea of the pit of fire, a neighbor volcano which it has almost engulfed in its swollen bulk, well illustrates the volcano built up by outpourings of lava from vents broken through its sides. ❋ Robert Sterling Yard (1903)
But purists can now order the California with a real six-speed manual, complete with clutch pedal, double-cone synchros with multiple pawl asymmetric geometry and an oil bath fork and lever system. ❋ Noah Joseph (2010)
* Triple-cone synchronizers for first, second and third gears and a double-cone synchronizer for fourth gear for optimized gearshift operation ❋ Unknown (2009)
The shortest-wavelength single - and double-cone opsin genes were never expressed, and the longest-wavelength genes were expressed ubiquitously. ❋ Christopher M. Hofmann Et Al. (2009)
Although there was some variation in single - and double-cone sensitivities within Lake Victoria, all Victorian taxa fell into the long-wavelength group. ❋ Christopher M. Hofmann Et Al. (2009)
To calculate average single - or double-cone sensitivities, peak spectral sensitivities for each opsin were weighted by the fraction of their expression in each cone type using the following equations: where fi is the relative expression and λ max values from heterologously expressed O. niloticus opsins (SWS1 = 360 nm, SWS2B = 425 nm, SWS2A = 456 nm, Rh2B = 472 nm, Rh2Aα+β = 523 nm [mean], and LWS = 560 nm) [63]. ❋ Christopher M. Hofmann Et Al. (2009)
As for the clustering of opsin expression values, we used the clValid [60] package to validate the number of single - and double-cone clusters (two to ten clusters) using the Dunn, Connectivity, and Silhouette measures of internal cluster support. ❋ Christopher M. Hofmann Et Al. (2009)
(B) Estimates of Lake Malawi single - and double-cone sensitivities suggest that these three clusters correspond to visual palettes sensitive to short -, medium -, and long-wavelength portions of the cichlid visible light spectrum. ❋ Christopher M. Hofmann Et Al. (2009)
When we estimated single - and double-cone sensitivities based on patterns of opsin expression, we found that the species fell into three distinct short -, middle -, and long-wavelength clusters. ❋ Christopher M. Hofmann Et Al. (2009)
We implemented both hierarchical clustering and cluster validation statistics in the R package clValid We calculated the average single - and double-cone sensitivities of all taxa in order to better understand how changes in gene expression might influence overall retinal sensitivity. ❋ Christopher M. Hofmann Et Al. (2009)
Rather, estimating single - and double-cone sensitivity allowed us to plot the data in a two-dimensional space to infer how changes in gene expression influence overall retinal sensitivity in a quantitative manner. ❋ Christopher M. Hofmann Et Al. (2009)
These single - and double-cone sensitivities were estimated based on two assumptions: (1) the visual pigment λ max for each gene is the same for all species; and (2) the chromophore is A1 (11 - cis retinal) for all species. ❋ Christopher M. Hofmann Et Al. (2009)
Thus, our results suggest that regulatory changes in opsin gene expression have generated diverse sets of single - and double-cone sensitivities. ❋ Christopher M. Hofmann Et Al. (2009)
[65] to test the hypothesis that opsin gene expression and the resulting single - and double-cone sensitivities differ among Lake Malawi cichlids with different foraging modes or macrohabitat preferences. ❋ Christopher M. Hofmann Et Al. (2009)
[29] to estimate average single - and double-cone sensitivities for each species [30]. ❋ Christopher M. Hofmann Et Al. (2009)
Each point or column represents a different taxon (see Gene expression profiles and single - and double-cone sensitivities form three clusters. ❋ Christopher M. Hofmann Et Al. (2009)
These analyses compared relative opsin expression and single - and double-cone sensitivity to foraging mode and habitat among cichlid species from Lake Malawi using three different phylogenetic hypotheses ( ❋ Christopher M. Hofmann Et Al. (2009)
Guy 1: "What are you getting as a [sundae]?"
Guy 2: "I think I want the Double Shot Cone."
Guy 1: "But dude, you can't get that, it's on the kids' menu."
Guy 2: "[I know but] it looks SOOOOOO [GOOOOD]!" ❋ Batfreak (2010)