Epitope

Word EPITOPE
Character 7
Hyphenation N/A
Pronunciations N/A

Definitions and meanings of "Epitope"

What do we mean by epitope?

A localized region on the surface of an antigen capable of eliciting an immune response and of combining with a specific antibody to counter that response. noun

That part of a biomolecule (such as a protein) that is the target of an immune response noun

The site on the surface of an antigen molecule to which an antibody attaches itself noun

That part of a biomolecule (such as a protein) that is the target of an immune response

Synonyms and Antonyms for Epitope

  • Synonyms for epitope
  • Epitope synonyms not found!!!
  • Antonyms for epitope
  • Epitope antonyms not found!

The word "epitope" in example sentences

This recombinant protein was used since deletion of the internal epitope between amino acids 433 and 447, called epitope 1443, increases the production of neutralizing antibodies in mouse models of infection ❋ Laura Ratier Et Al. (2008)

T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease. ❋ Donna Jackson Nakazawa (2008)

Taking into account the circulating B cells and calculating the quantity of antibody per immunologically-distinct epitope, the conclusion was that an infant could mount a response to the antigens present in “10 000 vaccines”. ❋ Unknown (2008)

Although these features are inconsequential for the use of DsRed as a reporter of gene expression, the usefulness of DsRed as an epitope tag is severely limited. ❋ Unknown (2005)

Unfortunately, this protein is an obligate tetramer, making it less suitable fur use as an epitope tag than PA-GFP. ❋ Unknown (2005)

HVTN said the vaccine candidate was a multi-epitope vaccine developed by Epimmune, a San Diego-based pharmaceutical company. ❋ Unknown (2003)

The library's diversity is expected to result in antibodies against previously inaccessible target molecules and unique epitope coverage. ❋ Unknown (2011)

Monoclonal antibodies are highly specific, being directed against a single antigenic epitope. ❋ Unknown (2010)

All cTnI constructs were derived from the full-length rodent sequence and tagged with C-terminal Flag epitope (DYKDDDDK, Sigma) to distinguish the recombinant from the native cTnI; while, the Tm mutants were engineered into the full-length human Tm ❋ Jennifer Davis Et Al. (2010)

Examples of terminal insertions include humanized anti-IL-10 antibody with an N-terminal methionyl residue or the antibody fused to an epitope tag. ❋ Unknown (2010)

Thus, the eliciting antigen may be a single epitope, multiple epitopes, or the entire protein alone or in combination with one or more immunogenicity enhancing agents known in the art. ❋ Unknown (2010)

G159D cTnC was subcloned into the pDC315 AdMax shuttle vector (Microbix Biosystems Inc.) with and without an HA (Hemagglutinin) epitope tag as previously described ❋ Jennifer Davis Et Al. (2010)

To screen for antibodies which bind to the epitope on human IL-10 bound by an antibody of interest (e.g., those which block binding of the cytokine to its receptor), a routine cross-blocking assay such as that described in ANTIBODIES, A LABORATORY MANUAL, Cold ❋ Unknown (2010)

There is no specific epitope through which the activity can be explained, and ❋ Unknown (2010)

As used herein, the term "portion" refers to the minimal number of amino acids or nucleic acids, as appropriate, to constitute an immunogenic epitope of the antigen of interest. ❋ Unknown (2010)

Using the ProteOn system five high-affinity mAbs were identified, four of which were purified, their kinetic binding constants reanalysed and epitope mapping performed using Bio-Rad's 'One-shot Kinetics' approach. [email protected] (2010)

Most often, target proteins (baits) are purified along with their interaction partners (preys) through an epitope tag-based affinity chromatography step. ❋ Unknown (2010)

In this report the importance of antibody subclass and epitope specificity in the outcome of these passive immunization experiments are discussed. ❋ Irosoki Eslava (2010)

Various epitope-tagged isoforms of GPR110 were expressed in cell lines and assayed by western blotting to determine cleavage, surface localization, and secretion patterns. ❋ Amy Lum (2010)

Cross Reference for Epitope

What does epitope mean?

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