Glycolytic

Its role surfaced only gradually as Meyerhof's group patiently broke the glycolytic pathway into its individual steps and analyzed them. ❋ Unknown (2010)

Indeed, much of the critical identification of glycolytic enzymes in Meyerhof's laboratory was done in connection with experiments on yeast. ❋ Unknown (2010)

This would be significant later on in working out the full details of the glycolytic pathway. ❋ Unknown (2010)

Meyerhof and his colleagues in Heidelberg worked out step after step of the glycolytic pathway. ❋ Unknown (2010)

I was told design cannot explain why a glycolytic enzyme is part of the degradosome. ❋ Unknown (2008)

Just to complicate matters a bit, α-actinin-2 is also differently spliced in different tissues, producing a couple of isoforms from a single gene. α-actinin-3 is not found in the brain or heart, but only in skeletal muscle and specifically in type II fast glycolytic muscle fibers. ❋ Unknown (2009)

They report that a single switch in a splice isoform of the glycolytic enzyme pyruvate kinase is necessary for the shift in cellular metabolism to aerobic glycolysis and that this promotes tumorigenesis. ❋ Unknown (2008)

It is suggested that ad libitum feeding conditions decrease NAD availability which also decreases metabolism of the triose phosphate glycolytic intermediates, glyceraldehyde-3-phosphate and dihydroxyacetone-phosphate, which can spontaneously decompose into methylglyoxal MG. ❋ Unknown (2007)

Other studies multiple have demonstrated that the intermediate products in glycolysis drive the production of MG and show that when the total time subjects are in the glycolytic state is lessened, so is the production of MG. ❋ Unknown (2007)

The low levels of NAD and pyruvate caused by net synthesis of 2, 3-bisPglycerate shifted the equilibrium of the glycolytic intermediates toward high triose-Ps21. ❋ Unknown (2005)

When I felt that we understood control of the red cell glycolytic system my attention returned to mechanism questions: ATP driven synthetases, reactions such as glutamine synthetase (gluamate + NH3 + ATP – glutamine + ADP + Pi) may be written to go in three steps: ATP + E - ❋ Unknown (2005)

A key adaptation allowing a continued high level of glycolysis in crucian carp is the production and excretion of ethanol as the glycolytic end-product, thereby avoiding lactate self-poisoning. ❋ Unknown (2006)

Thus, in birds and crocodiles, the glycolytic enzyme lactate dehydrogenase B LDHB serves two distinct functions as both an enzyme and as Epsilon-crystallin, a major constituent of the lens. ❋ Unknown (2005)

Much of the lactate is then used immediately by muscle cells with a high oxidative potential and lower glycolytic potential (slow-twitch fibers) while much of the rest is used by the muscle with the highest aerobic potential (the heart). ❋ Unknown (2005)

The string of experimental success at the KWImF led to the first complete determination of a metabolic pathway - the glycolytic or Embden-Meyerhof ❋ Unknown (2001)

Minkowski in the complete account of his researches, published in 1893, considered the antidiabetic function of the pancreas to be dependent upon its acting as a ductless gland, and no doubt he had in mind that it performed this through an internal secretion, although the positive statement that such exists was first made by Lepine, who thought that it took the form of a glycolytic enzyme. ❋ Unknown (1965)

In 1925 Meyerhof succeeded in extracting the glycolytic enzyme system from muscle, retracing a pathway which Buchner and Harden and Young had explored in yeast. ❋ Unknown (1965)

Suppose the internal secretion of a gland (_e. g._ glucose for the liver, glycolytic for the ferment for the pancreas) is the physiological excitant for the gland. ❋ J. T. Cunningham (1897)

The glycolytic pathway has become of renewed interest in cancer. ❋ Unknown (2010)