Gnotobiotic

When the researchers transferred bacteria from obese mice into so-called gnotobiotic mice, which were raised in a sterile environment and had no bacteria in their guts, the mice gained more weight than did those receiving a similar amount of bacteria from lean mice, even though they were fed the same diet.

During quality assessment, 233 references were excluded because they failed to report design features that limit the introduction of bias or were conducted in a non-target population such as gnotobiotic, neonatal, nursery, or recently weaned pigs and sows. ❋ Unknown (2008)

Gordon JI (2006) A humanized gnotobiotic mouse model of host-archaeal-bacterial mutualism. ❋ Franck Thuny Et Al. (2010)

PCV2 was later isolated from lesions of affected pigs and the first experimental reproduction of PMWS clinical signs and lesions was completed using PCV2 and porcine parvovirus (PPV) co-infection in gnotobiotic pigs. ❋ Unknown (2010)

This position, supported under the P30 mechanism, is designed to attract appropriately trained postdoctoral fellows or junior investigators (no previous tenure track appointment) to explore one or more of the following research areas: (1) interplay of innate/adaptive immune systems and bioflims, possibly using germfree/gnotobiotic models; (2) mucosal vaccinology; or (3) autoimmunity. ❋ Unknown (2009)

Turnbaugh, P. J., et al. The effect of diet on the human gut microbiome: A metagenomic analysis in humanized gnotobiotic mice. ❋ Unknown (2009)

This research involved several different experiments, all of which used 'gnotobiotic mice'.

To make the mouse model, the researchers put microbes from human faecal matter into the guts of gnotobiotic mice to establish a human-like gut colony.

Gordon and Turnbaugh found that they could transfer bacteria from human intestines into gnotobiotic mice, which were fed a low-fat, plant-rich diet in the weeks before the bacteria were transplanted and for a month afterward.

(iv) protect gnotobiotic Artemia shrimp against virulent Vibrio harveyi BB120. ❋ Unknown (2008)