"In recent years it has become apparent that heterochromatin is critical for many essential functions." ❋ Unknown (2007)
"These modifications cause parts of chromosomes to condense into so-called heterochromatin, burying the regulatory regions of p53 target genes deep within," says graduate student and co-first author Fanny E. Estermann. ❋ Unknown (2010)
In general, C-bands and G-bands are complexed with proteins and RNAs to give a more compact organization called heterochromatin, whereas R-bands have a more open conformation referred to as euchromatin. ❋ Unknown (2009)
In contrast, a major part of the, non-active 'more compacted DNA regions, termed heterochromatin, are located in the nuclear periphery. ❋ Unknown (2009)
The study concentrates on understanding material called heterochromatin that assembles on centromeric sequences.
In other words, the so-called "heterochromatin" with which the cytologist deals in studying mitotic chromosomes is a quite different thing from, although in the neighborhood of, the heterochromatin proper having the above described complex of properties. ❋ Unknown (1964)
~ Exploring the Dark Matter of the Genome -- "Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." ❋ William Harryman (2007)
In non-dividing cells, DNA is associated with proteins to form the so-called chromatin, with more condensed "heterochromatin" at the periphery and less condensed "euchromatin" in the interior.
Certain regions are kind of stuffed away into something called heterochromatin, " ❋ Unknown (2009)
"Most researchers thought heterochromatin had little or no function, because it appeared to lack the protein-coding genes that occur so richly in the chromosomes 'more accessible and better-studied euchromatin," says Karpen, a senior scientist in Berkeley Lab's Life Sciences Division and an adjunct professor of cell and molecular biology at the University of California at Berkeley. ❋ Unknown (2007)
In non-dividing cells, DNA is associated with proteins to form the so-called chromatin, with more condensed “heterochromatin” at the periphery and less condensed “euchromatin” in the interior. ❋ Unknown (2009)
The central portion of their nuclei is occupied by a large mass of heterochromatin, while transcription factors that control the activity of genes are enriched at the nuclear periphery. ❋ Unknown (2009)
Methylation of histone H3 on lysine 9 and accumulation of chromodomain proteins, hallmarks of heterochromatin, also occur specifically on sequences undergoing elimination and are dependent on the small RNAs. ❋ Unknown (2006)
These findings contribute to a new paradigm of chromatin biology: regulation of heterochromatin formation by RNAi-related mechanisms in eukaryotes. ❋ Unknown (2006)
Like dark matter in the universe, the true nature of heterochromatin was unknown. ❋ William Harryman (2007)
In particular, the fact that repeat elements serve either as initiators or boundaries for heterochromatin domains and provide a significant fraction of scaffolding/matrix attachment regions S/MARs suggests that the repetitive component of the genome plays a major architectonic role in higher order physical structuring. ❋ Denyse O (2005)
In the third species, blocks of heterochromatin are distributed all along the chromosomes. ❋ Unknown (1983)
The elimination process is associated with formation of rings of DNA cut out from the heterochromatin (35). ❋ Unknown (1983)