Hexamer

The human telomere is a hexamer TTAGGG repeated thousands of times. and ❋ Unknown (2010)

This insulin hexamer corresponds with the unit cell in the rhombohedral crystals first investigated and is the asymmetric unit in the monoclinic form which appears in the presence of phenol. ❋ Unknown (1964)

The fourth beta-hairpin, however, is located on the exterior of the hexamer, near the exit of the putative side channels and next to the ATP binding pocket. ❋ Aaron Brewster (2010)

The same hexamer can be shown multiple times if it can be mapped on more than one miRNAs. ❋ Panagiotis Alexiou Et Al. (2010)

Hexamer 3 is not taken into account for the calculation of the combinatorial hexamer score. ❋ Panagiotis Alexiou Et Al. (2010)

A similar orientation for the hexamer was proposed previously ❋ Mahiuddin Ahmed (2010)

Genes containing the hexamer of interest (A), or targeted by the miRNA of interest (C) are mapped on KEGG pathways and the most significantly overrepresented pathways can be identified by their corresponding p-values. doi: 10.1371/journal. pone.0009171.g004 ❋ Panagiotis Alexiou Et Al. (2010)

The structure reveals a total of four beta-hairpins per subunit, three of which are located within the main channel or side channels of the ssoMCM hexamer model generated based on the symmetry of the N-terminal ❋ Unknown (2010)

Keeping the weight for the 'seed' hexamer constant at 1, we have determined that for a weight of hexamer 1 set to 0.6, no value of hexamer 3 will improve the identification of the correct miRNA. ❋ Panagiotis Alexiou Et Al. (2010)

Therefore DIANA-mirExTra provides a combinatorial hexamer score in which the - lnp value of hexamer 1 is multiplied by a weight of ❋ Panagiotis Alexiou Et Al. (2010)

The hexamer in position 2 has been found as the top ranking hexamer with the maximum possible - lnp value in all datasets. ❋ Panagiotis Alexiou Et Al. (2010)

Kolakofsky D, Pelet T, Garcin D, Hausmann S, Curran J, et al. (1998) Paramyxovirus RNA synthesis and the requirement for hexamer genome length: the rule of six revisited. ❋ Arthur S. Samuel Et Al. (2010)

Another option provided by DIANA-mirExTra is the use of miRNA target prediction scores instead of hexamer frequencies on a 3′UTR. ❋ Panagiotis Alexiou Et Al. (2010)

Random hexamer primed reverse transcription reactions were performed from 400 ng of total RNA in a 20 µl setup using TaqMan® Reverse Transcription reaction (Applied Biosystems). ❋ Hans-Christian Ingerslev Et Al. (2010)

However, more than one miRNAs may share the same seed hexamer. ❋ Panagiotis Alexiou Et Al. (2010)

In a more sophisticated approach, they used the Wilcoxon Rank Sum test to compare hexamer frequencies between deregulated and unchanged genes between the two conditions. ❋ Panagiotis Alexiou Et Al. (2010)

Thus, while the importance of the hexamer phasing positioning is well-known for cis-acting signals involved in RNA replication ❋ Arthur S. Samuel Et Al. (2010)

The weight for hexamer 1 is on the Y axis, for hexamer 2 is held constant at a value of 1, and for hexamer 3 is on the X axis. ❋ Panagiotis Alexiou Et Al. (2010)

For each possible hexamer, the occurrences on the 3′UTRs of changed and unchanged genes are counted. ❋ Panagiotis Alexiou Et Al. (2010)

While all of the APMV genomes conform to the rule of six, there was no consistent pattern to the hexamer phasing positions of the GS and GE signals other than that of the N gene being at position 2 in all nine serotypes. ❋ Arthur S. Samuel Et Al. (2010)