Histone

Word HISTONE
Character 7
Hyphenation N/A
Pronunciations /ˈhɪstəʊn/

Definitions and meanings of "Histone"

What do we mean by histone?

Any of several small, basic proteins most commonly found in association with the DNA in the chromatin of eukaryotes. noun

Any of various simple water soluble proteins that are rich in the basic amino acids lysine and arginine and are complexed with DNA in the nucleosomes of eukaryotic chromatin. noun

A simple protein containing mainly basic amino acids; present in cell nuclei in association with nucleic acids noun

Any of various simple water-soluble proteins that are rich in the basic amino acids lysine and arginine and are complexed with DNA in the nucleosomes of eukaryotic chromatin.

Synonyms and Antonyms for Histone

  • Synonyms for histone
  • Histone synonyms not found!!!
  • Antonyms for histone
  • Histone antonyms not found!

The word "histone" in example sentences

There is a sophisticated code, known as the histone code, that directs the decisions as to which parts of the DNA sequence are transcribed into mRNA and which are not. ❋ M.D. Henry Emmons (2010)

Typically, the gossamer thread of DNA is wound around a spool of protein called histone; when this second class of enzymes strips away part of the packaging, the DNA becomes so tightly wound up that it can't loosen up enough to be read by the cell. ❋ Unknown (2009)

A group of agents called histone deacetylase inhibitors can help here, says Sharon Lewin, director of the infectious-diseases unit at Alfred Hospital in Melbourne, who is about to start a clinical trial of a histone-deacetylase inhibitor called SAHA. ❋ Unknown (2011)

"In addition to this, we have also shown that when the neuroblastoma and breast cancer cells are treated with a new class of anti-cancer drugs called histone deacetylase inhibitors (HDACIs), they are able to turn the TG2 gene back on, which then inhibits tumour growth." ❋ Unknown (2010)

The interaction between the active form of the frataxin gene and the inactive (silenced) form is mediated by enzymes called histone deacetylases (HDAC). ❋ Unknown (2010)

While they are powerful killers of some breast cancer cells, new drugs called histone deacetylase inhibitors, or HDAC inhibitors, also increase self-digestion, or autophagy, in surviving, mega-stressed cells. ❋ Ani (2010)

Together, they designed and used a DNA-cutting enzyme called a zinc finger nuclease to chemically tag histone H3. 3 and distinguish it from other histone proteins in mouse embryonic stem cells. ❋ Unknown (2010)

They showed how cocaine affects an epigenetic process (a process capable of influencing gene expression without changing a gene's sequence) called histone methylation. ❋ Unknown (2010)

Cross Reference for Histone

  • Histone cross reference not found!

What does histone mean?

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