Hydrolase

Enzymes either tear apart molecules (called hydrolase) or put them together (called conjugase). { ❋ Unknown (2010)

The region includes genes encoding a CoA-dependent methylmalonate semialdehyde dehydrogenase (dntE), a putative NADH-dependent dehydrogenase (ORF13), and a bifunctional isomerase/hydrolase (dntG). ❋ Unknown (2010)

Anna Helgadottir et al., “A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction,” Nature Genetics 38 2006, 68–74. ❋ Kevin Davies (2010)

Sebenarnya gen yang berperan dalam enzim ini masih belum diketahui. α -Arabinosidase merupakan salah satu hydrolase yang membongkar pektin seperti pada PME (pectinmethylesterase) dan PAE (pectin acetylesterase). ❋ Unknown (2010)

Selain enzim hydrolase di atas, ada gen yang berperan juga dalam proses ripening fruit dan softening fruit, yaitu Expansin. ❋ Unknown (2010)

A putative novel alpha/beta hydrolase ORFan family in Bacillus. ❋ Unknown (2006)

For example MG125 white bar in Fig 2 of Glass et al., 2006, is of unknown function, but is a member of the Cof hydrolase family, and has many homologs in a wide variety of bacteria . ❋ Unknown (2006)

Using improved fold recognition software, and a larger database of fold family structures, they have found that in Bacillus sp, some related ORFans are members of the of the alpha/beta hydrolase superfamily, and most likely derive from the haloperoxidases Siew et al., 2005. ❋ Unknown (2006)

Called leukotriene A4 hydrolase, the gene is involved in the synthesis of leukotrienes, agents that maintain a state of inflammation. ❋ Steve Sailer (2005)

K172 indicated that the 392-amino acid-residue-long bacterial enzyme 6-aminohexanoic acid linear oligomer hydrolase involved in degradation of nylon oligomers is specified by an alternative open reading frame of the preexisted coding sequence that originally specified a 472-residue-long arginine-rich protein. sanjait ❋ Unknown (2005)

The lab also detected trace quantities of the gamma-amino metbionine hydrolase. ❋ Crichton, Michael, 1942- (1991)

Infinity's programs in the inhibition of the Hedgehog pathway, the Hsp90 chaperone system, phosphoinositide-3-kinase and fatty acid amide hydrolase are evidence of its innovative approach to drug discovery and development.

Infinity's programs in the inhibition of the Hedgehog pathway, the Hsp90 chaperone system, fatty acid amide hydrolase, and phosphoinositide-3-kinase are evidence of its innovative approach to drug discovery and development. ❋ Unknown (2011)

Ap4A-hydrolase is responsible for metabolizing the "allarmone" nucleotide Ap4A and therefore likely involved in regulation of cell proliferation, DNA replication, RNA processing, apoptosis and DNA repair. ❋ Natalia Vasilenko (2010)

The interaction was confirmed by co-immunoprecipitation from cultured human cells transiently expressing V5-His tagged 7a and HA tagged Ap4A-hydrolase. ❋ Natalia Vasilenko (2010)

The interaction between 7a and Ap4A-hydrolase was identified using yeast two-hybrid screening. ❋ Natalia Vasilenko (2010)

Human tissue culture cells transiently expressing 7a and Ap4A-hydrolase tagged with EGFP and Ds-Red2 respectively show these proteins co-localize in the cytoplasm. ❋ Natalia Vasilenko (2010)