Hypochromic Wiki - What is the hypochromic?
Hypochromic anemia, or Hypochromic anaemia, is a generic term for any type of anemia in which the red blood cells (erythrocytes) are paler than normal. (Hypo- refers to less, and chromic means color.) A normal red blood cell will have an area of pallor in the center of it; it is biconcave disk shaped. In hypochromic cells, this area of central pallor is increased. This decrease in redness is due to a disproportionate reduction of red cell hemoglobin (the pigment that imparts the red color) in proportion to the volume of the cell. Clinically the color can be evaluated by the Mean Corpuscular Hemoglobin (MCH) or Mean Corpuscular Hemoglobin Concentration (MCHC). The MCHC is considered the better parameter of the two as it adjusts for effect the size of the cell has on its color. Hypochromia is clinically defined as below the normal MCH reference range of 27-33 picograms/cell in adults or below the normal MCHC reference range of 33-36 g/dL in adults.Red blood cells will also be small (microcytic), leading to substantial overlap with the category of microcytic anemia. The most common causes of this kind of anemia are iron deficiency and thalassemia. Hypochromic anemia was historically known as chlorosis or green sickness for the distinct skin tinge sometimes present in patients, in addition to more general symptoms such as a lack of energy, shortness of breath, dyspepsia, headaches, a capricious or scanty appetite and amenorrhea..
What does the word hypochromic mean? Find synonyms, antonyms and the meaning of the word hypochromic in our free online dictionary! Find words starting with hypochromic and anagrams of hypochromic.
Definitions of "hypochromic"
- Describing a decrease in the intensity of a spectral band due to a change in the molecular environment adjective
- Having a lower than normal amount of hemoglobin in the red blood cells adjective
The word "hypochromic" in example sentences
In iron deficiency the cells are small and contain very little haemoglobin and they are called hypochromic, microcytic cells.. 
In microcytic anemia, the red blood cells (erythrocytes) are usually also hypochromic, meaning that the red blood cells are paler than usual.. [Citizendium, the Citizens' Compendium - Recent changes [en]]
Again, we find it effective in enhancing the rate of hemoglobin formation in the hypochromic anemias treated with iron.. [William P. Murphy - Nobel Lecture]
Clearly such disturbances are involved in the production of iron deficiency resulting in certain types of hypochromic anemia.. [George R. Minot - Nobel Lecture]
For the treatment of pernicious and hypochromic anaemia and for granulocytopenia he used intramuscular injections of extract of liver and he was associated with George Richards Minot and George Hoyt Whipple in work on pernicious anaemia and the treatment of it by means of a diet of uncooked liver.. [William P. Murphy - Biography]
In this study, low vitamin D levels at baseline were significantly associated with increased risk of HIV disease progression, severe anemia, and hypochromic microcytosis in HIV-infected Tanzanian women.. [PLoS ONE Alerts: New Articles]
The red blood cells become smaller (microcytic) and pale (hypochromic).. 
Typically, therefore, anemia of this category is described as "microcytic, hypochromic anemia".. [Citizendium, the Citizens' Compendium - Recent changes [en]]
Slide 47: Adverse Drug Effects in Therapeutic Use Agents primarily affecting blood constituents (Y44) Iron and other anti-hypochromic anemia preparations . [Recently Uploaded Slideshows]
Acid-base equilibrium hypochromic iron-insufficiency anaemia pregnant women. [xml's Blinklist.com]
If two of the four α loci are affected, alpha thalassemia trait, type 1 erythropoiesis, though there is a mild microcytic hypochromic anemia.. [Citizendium, the Citizens' Compendium - Recent changes [en]]
If both have thalassemia mutations, a severe microcytic, hypochromic anemia called. [Citizendium, the Citizens' Compendium - Recent changes [en]]
Transferrin saturation (TfS or TSAT), the hemoglobin content of reticulocytes or the percentage of hypochromic cells. [Citizendium, the Citizens' Compendium - Recent changes [en]]
(TfS or TSAT), the hemoglobin content of [[reticulocyte]] s or the percentage of hypochromic cells.. [Citizendium, the Citizens' Compendium - Recent changes [en]]
We show that zTERT knockdown causes hypochromic anemia at the onset of circulation, and that this is accompanied by the impaired differentiation of blood cells and their eventual apoptotic cell death leading to a severe reduction of hematopoietic cells ( 'pancytopenia'), during embryogenesis.. [PLoS ONE Alerts: New Articles]
This subsequently leads to the circulation of immature blood cells with hypochromic anemia due to a disruption of both primitive and definitive hematopoiesis without telomere shortening.. [PLoS ONE Alerts: New Articles]
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