Intron

We start from an organism that stores its genetic information in intron-less DNA and copies this to RNA as an intermediate to generate proteins. ❋ Unknown (2005)

The functional SNP that the scientists found was located on what is known as intron 6, a reference to a specific location within the gene that is typically overlooked when searching for a functionally relevant mutation. ❋ Unknown (2010)

But that could well be a real problem to solve – design me an intron depot so I can manage the traffic flow of nanoscopic drug delivery cars. ❋ Unknown (2009)

Sequence data from the mitochondrial cytochrome-b gene and the hypervariable control region as well as 7th intron of the nuclear fibrinogen gene show these 2 taxa to be reciprocally monophyletic. ❋ Unknown (2008)

They are separated by 13.8% sequence divergence (uncorrected) based on the 2 mitochondrial segments, and 4.2% based on the nuclear intron sequences. ❋ Unknown (2008)

Two nuclear intron regions (7th intron of the beta fibrinogen gene and thyrotropin) also were included, but showed limited genetic variation and no fixed differences between the 2 taxa. ❋ Unknown (2008)

I seem to recall reading a paper by King where she considers this possibility and did a good job of knocking it down (although the intron stuff mentioned in the ScienceDaily argument might resurrect this objection). ❋ Unknown (2008)

Gene mutation can occur at many levels - from single nucleotide polymorphisms, to the introduction of stop codons and longer stretches of DNA (whole genes, even) via intron/exon shuffling. ❋ Unknown (2009)

Third, the dsRNA had to correspond to the mature mRNA sequence; neither intron nor promoter sequences triggered a response. ❋ Unknown (2006)

None of this haploid/dipoloid meisosis stuff and none of this intron exon stuff just to confuse matters! ❋ Microbiologist Xx (2008)

Examination of DNA has shown genetic variation in both coding regions and in the non-coding intron region of genes. ❋ Unknown (2008)

In order to insert an intron into a functional gene, it has to be subsequently excised from the resulting RNA otherwise it will result in a non-functional protein. ❋ Unknown (2005)

Publishing in the journal Science, a group of international researchers have discovered that when it comes to gene structure, humans have barely evolved at all, as our genes have retained the high intron number of one of our ancient ancestors. ❋ Unknown (2005)

“The work presents a missing piece of the puzzle, which people studying intron evolution have been searching for in the past few years,” says Majewski. ❋ Unknown (2007)

“They present a strong validation for an intron-rich ancestor,” he says.. ❋ Unknown (2007)

Hence, in the case of DNA expression that eventually leads to the synthesis of a given polypeptide, geneticists might talk as if “the” gene included the intron (in which case they would be referring to the gene for the primary, preprocessed RNA) and yet also talk as if ❋ Waters, Ken (2007)

In addition, the plasmid must contain one or more eukaryotic genetic elements that control the initiation of messenger RNA transcription, a mammalian polyadenylation signal, an intron (optional), and a gene for co-selection in mammalian cells. ❋ Unknown (2005)

A remarkable twist to this conventional gene-duplication/sequence-divergence paradigm is the creation of a unique functional antifreeze glycoprotein (AFGP) sequence from partly non-coding DNA in Antarctic notothenioid fish, involving de novo duplications of a 9-nt sequence spanning an exon-intron junction of an ancestral trypsinogen-type protease gene to form a large, highly repetitive (ThrAlaAla)n coding region, and shedding most of the protease gene structure. ❋ Unknown (2007)