Isoprostane

Researchers can perform various experimental procedures and measure the release of isoprostanes in the urine and determine how much oxidative stress and free radical damage their procedure caused. 8-iso PGF is simply a specific isoprostane commonly used experimentally to determine the degree of oxidative stress/free radical damage. ❋ Unknown (2006)

In some studies, this isoprostane elevation has been shown to cause in vivo vasoconstriction and increase the aggregation of platelets ❋ Unknown (2010)

Significant reductions in 8-epi-isoprostane levels were found in the compartments except the choroid-sclera or plasma, indicating antioxidative activities of catechins in these tissues, concluded the team. ❋ [email protected] (2010)

And the eyes of the animals were then dissected into cornea, lens, retina, choroid-sclera, vitreous humor, and aqueous humor for analysis of catechins and 8-epi-isoprostane by HPLC-ECD and GC-NCI-MS, respectively. ❋ [email protected] (2010)

Quercetin also led to a noticeable decrease in the inflammation processes that are known to contribute to plaque formation (the production of isoprostane F2 and leukotriene B4, for example), while increasing production of nitrous oxide (NO), a vasodilator that helps prevent arteriosclerosis. ❋ Unknown (2010)

Urinary isoprostane was also significantly lowered after 200 mg/d DHA but was increased after 1600 mg/d. ❋ Unknown (2009)

What happened with isoprostane between 200 and 1600 mg? ❋ Unknown (2009)

At the end of the study, levels of markers of oxidative stress, including malondialdehyde and 8-isoprostane-F2 {alpha} decreased by 22 and 12 per cent, respectively. ❋ Unknown (2009)