The researchers then successfully prodded what they call keratinocyte-derived iPS cells or KiPS cells to distinguish them from fibroblast-derived iPS cells into becoming all the cell types in the human body, including heart muscle cells and dopamine-producing neurons, which are affected by Parkinson's disease. ❋ Unknown (2008)
Another effective treatment is a retinoid lotion, which regulates keratinocyte turnover and helps slough off the heaped-up, pointy dead skin cells. ❋ Ellen Marmur (2009)
Selenium sulfide has also been proven to suppress keratinocyte proliferation (excessive skin cell production), which leads to the itchiness and scaling characteristic of psoriasis vulgaris (plaque psoriasis). ❋ Unknown (2009)
Chi's management team to complete acquisition from Carilion Clinic Phase 1/2 human clinical trial of Symphogen's Sym004 initiated in the US Providing direct access to imaging test results may improve patient satisfaction, but increase anxiety as well Role of membrane cholesterol in late keratinocyte differentiation analyzed ❋ Editors (2010)
Besides keratinocyte biology, psoriasis is marked by complex pattern of immune system activation, including expansion of CD11c, upregulation of interferon signalling, and influx of T cells. ❋ Malgorzata Romanowska Et Al. (2010)
On the other hand, it regulates keratinocyte differentiation [10]. ❋ Malgorzata Romanowska Et Al. (2010)
GWAS, genome-wide association study; KC, keratinocyte; KIR, killer immunoglobulin-like receptors; LCE, late cornified envelope; LD, linkage disequilibrium; MHC, major histocompatibility complex; pDC, plasmacytoid dendritic cells; PsA, psoriatic arthritis; ❋ James T Elder (2010)
Our findings identify PPARβ/δ as a molecular link between metabolism, keratinocyte differentiation, and the epidermal immune response. ❋ Malgorzata Romanowska Et Al. (2010)
Histologically, they are marked by increased keratinocyte proliferation, as well as a block in terminal differentiation. ❋ Malgorzata Romanowska Et Al. (2010)
Romanowska M, al Yacoub N, Seidel H, Donandt S, Gerken H, et al. (2008) PPARdelta enhances keratinocyte proliferation in psoriasis and induces heparin-binding EGF-like growth factor. ❋ Malgorzata Romanowska Et Al. (2010)
Kaufman CK, Sinha S, Bolotin D, Fan J, Fuchs E (2002) Dissection of a complex enhancer element: maintenance of keratinocyte specificity but loss of differentiation specificity. ❋ Malgorzata Romanowska Et Al. (2010)
Tan NS, Michalik L, Noy N, Yasmin R, Pacot C, et al. (2001) Critical roles of PPAR beta/delta in keratinocyte response to inflammation. ❋ Malgorzata Romanowska Et Al. (2010)
