Ligands

The chemicals that attach to receptors are called ligands, from the Latin word ligandus, “that which bonds.” ❋ M.D. Dharma Singh Khalsa (2001)

On the more inorganic side, we have systematically explored the geometries, polytopal rearrangement and substitution site preferences of five, six, seven and eight coordination, the factors that influence whether certain ligands will bridge or not, the constraints of metal-metal bonding, and the geometry of uranyl and other actinide complexes. ❋ Unknown (1982)

They looked at the correlation of ligand structure with enzyme domains, and propose a method to identify cognate ligands, that is, ligands that are present in vivo and are required for a functional metobolome. ❋ Egon Willighagen (2007)

Receptors are proteins whose amino acid chains fold in such a way as to produce a pocket where particular small molecules hereafter called ligands bind. ❋ Unknown (2006)

Some dietary chemicals, called ligands, peel off and bind to proteins, effectively “turning on” certain genes. ❋ Susan Mitchell Ph.D. (2005)

EGFR is nestled into the cell membrane on the surface of human cells where, after it gets activated by molecules called ligands, causes cells to divide. ❋ Unknown (2009)

The Menlo Park research organization will study imaging agents called ligands, which are intended to be injected before brain scans like positive emission tomography (PET), magnetic resonance imaging (MRI) and other similar processes. ❋ Unknown (2009)

This problem is particularly acute for tightly integrated molecular systems that consist of many interacting parts, such as ligands, receptors, and the downstream regulatory factors with which they interact. ❋ Unknown (2004)

These molecules act as "ligands" for arsenic, meaning that they form a complex with it. ❋ Unknown (2009)

The similar binding mode is paralleled by the remarkable structural and electrostatic similarity between the ligands, which is pointed out by the calculated Tanimoto coefficients for the electrostatic potential (Te) and shape (Ts) [60] between each of them (values ranging between 0. 7±0.3 and 0. 8±0.1 for Te and Ts, respectively, see ❋ Fernando E. Herrera Et Al. (2008)

After many more years and discoveries, better dyes descended from BAPTA** became the most popular way of seeing endogenous intracellular Ca2+ signals, screening for ligands and receptors linked to Ca2+ signaling, and imaging neuronal activity microscopically. 10 ❋ Unknown (2009)

The Pearson theory of hard and soft ligands and metals was new and fashionable at the time, so Prof. Kline wanted me to find out if thiocyanate could simultaneously bind with its "soft" sulfur to a soft metal and its "hard" nitrogen to a hard metal, e.g. PhHg – SCN – Cr (III). ❋ Unknown (2009)