The decline in strokes in older adults is almost certainly due to better treatment of hypertension, the leading cause of stroke, and to a lesser extent the modification of other risk factors for cardiovascular disease, such as lipid-lowering with statin drugs. ❋ M.D. David Katz (2011)
Pharmacological obesity trials regularly show high-rates of discontinuation (around 20-40% at 12 months), not very different from that seen in real life for blood pressure or lipid-lowering medications. ❋ Unknown (2008)
Anthocyanins may also have insulin-like properties “that contribute to improved metabolic function and lipid-lowering effects,” according to the researchers. ❋ Unknown (2010)
The present trial was designed to evaluate the effect of cholesterol lowering with simvastatin on mortality and morbidity in patients with coronary heart disease CHD. 4444 patients with angina pectoris or previous myocardial infarction and serum cholesterol 5.5-8.0 mmol/L on a lipid-lowering diet were randomised to double-blind treatment with simvastatin or placebo. ❋ Unknown (2009)
A pooled analysis of 8 randomized trials in primary prevention populations showed that statins did not reduce overall mortality, indicating that lipid-lowering therapy with statins should not be prescribed for true primary prevention in women of any age or in men older than 69 years. ❋ Unknown (2009)
Despite the administration of a statin, many patients require additional lipid-lowering therapy because their target lipid-level goals are not reached or they have a cardiovascular event. ❋ Unknown (2009)
In light of the controversy surrounding lipid-lowering treatment for reduction of mortality among primary prevention populations, we undertook the present study to evaluate the effect of statin therapy in a large and diverse cohort of patients treated for dyslipidemia in a single health maintenance organization. ❋ Unknown (2009)
Now it seems that among patients with stroke and LDL levels already under 100 -- with or without statins -- those ON the statin lipid-lowering meds had better oucomes. ❋ 1 Dinosaur (2009)
Similar to prescription lipid-lowering drugs, red yeast should be avoided by anyone who has a liver problem or who drinks heavily. ❋ Earl Mindell (2008)
Known as guggulipid, this natural plant extract has become a popular lipid-lowering agent in the United States. ❋ Earl Mindell (2008)
Vytorin is also indicated for the reduction of elevated total cholesterol and LDL cholesterol in patients with homozygous familial hypercholesterolemia, as an adjunct to other lipid-lowering treatments (e.g. LDL apheresis) or if such treatments are unavailable. ❋ Unknown (2008)
In clinical trials, there was no increased incidence of myopathy (muscle pain) or rhabdomyolysis (muscle breakdown) associated with Zetia; however myopathy and rhabdomyolysis are known adverse reactions to statins and other lipid-lowering drugs. ❋ Unknown (2008)
