Lipodystrophic

In these lipodystrophic mice, however, the adipose tissue did not release the excess fatty acids and the dietary fat accumulated in the liver. ❋ Unknown (2009)

What is surprising about this, Dr. Garg said, is that the amount of fat stored in the liver dropped substantially when researchers put the lipodystrophic mice on a fat-free diet. ❋ Unknown (2009)

Scientifically, it creates a unified framework to help to explain how diabetes can occur in both obese and lipodystrophic states. ❋ Unknown (2008)

However, the majority of type 2 diabetic individuals are not lipodystrophic but are actually obese. ❋ Unknown (2008)

The A / Zip fatless mouse and the adipose-nSREBP1c TG mouse both have impaired adipogenesis, which results in a lipodystrophic animal. ❋ Unknown (2008)

The adipose tissue expandability hypothesis suggests that the insulin resistance found in lipodystrophic and obese individuals is caused by the same pathogenic mechanism of impaired adipose tissue expansion capacity, even if the underlying cause and degree of impairment in adipose tissue expansion may be very different. ❋ Unknown (2008)

First, it is well documented that lipodystrophic individuals develop severe insulin resistance [ ❋ Unknown (2008)