Lipophilicity

For example, absorption of inhaled metallic Hg in blood is very high, and 70 – 80% is retained; its in vivo distribution is similar to that of organic Hg; and it is readily transferred through the placenta and blood – brain barrier because of its lipophilicity (ATSDR 1999b). ❋ Unknown (2009)

Also contributing to this is its lipophilicity; indole sticks to skin like mad. ❋ Unknown (2006)

Not only has BSN increased water and lipophilicity, hydrogen ion buffering has also been addressed with the addition of Beta-Alanine. ❋ Amp;34;Nutrition (2010)

In order to further increase the lipophilicity of BPs (and their entering into the cells), we synthesized new aromatic 1-hydroxymethylene-1,1-bisphosphonic acids containing phenyl or halogen phenyl ring in their side chains. ❋ Unknown (2009)

In accordance, characterisation of the hydrophilicity demonstrated a shift toward lipophilicity of the BP7033Br ALK compound (Log P values of − 0.75 versus − 031, respectively). ❋ Unknown (2009)

Jaroszewicz I, Platts JA, Kuduk-Jaworska J (2008) Calculation of lipophilicity for Pt (II) complexes: experimental comparison of several methods. ❋ Unknown (2009)

The unrelated to relative lipophilicity or ambient drug clinical use of clozapine levels. ❋ Martins0105 (2009)

Similarly, oral melatonin has an lipophilicity, usually measured as the octanol/absolute bioavailability of about 15% maximum water distribution coef fi cient when the aqueous and was eventually withdrawn in the United King - phase is buffered at pH 7.4. ❋ Martins0105 (2009)

If a drug reasonable lipophilicity, are the best candidates for cannot be dissolved in a concentrated manner in a transdermal delivery. ❋ Martins0105 (2009)

Biochim Biophys Acta 1712: 197-211. van Balen GP, Martinet CM, Caron G, Bouchard G, Reist M, et al. (2004) Liposome/water lipophilicity: methods, information content, and pharmaceutical applications. ❋ Marco M. Domingues Et Al. (2009)

(0. 3-7\% in humans) due to chelation of metal ions by phosphonic acid group inside the digestive lumen, poor membrane permeability due to poor BP lipophilicity as well as strong uptake by bone tissue ❋ Unknown (2009)

[Lipophile]=Someone who is [sexually] attraced to [thick] people. ❋ Nikkan_hanil (2004)

AHHH! RUN FROM THE [FAT ASIAN] [LIPOPHILE]! HES A RAPIST AND [PREDATOR]! ❋ SaggingDededeeznutz (2019)