Lymphomagenesis

Transgenic mice as an in vivo model of lymphomagenesis. ❋ Unknown (2007)

The contribution of Nfkb2 to Myc-driven lymphomagenesis was tested in vivo, where Nfkb2 loss was shown to accelerate lymphoma development in Eu-Myc transgenic mice, by impairing Myc's apoptotic response. ❋ Unknown (2010)

Note that this large study presented evidence for an important role of hepatitis B virus infection in lymphomagenesis. ❋ Unknown (2010)

MALT lymphomagenesis can be reproduced by experimental infection of BALB ❋ V J Craig (2010)

The contribution of Nfkb2 to Myc-driven apoptosis, proliferation, and lymphomagenesis was tested genetically in vivo. ❋ Ulrich Keller (2010)

Nfkb2 is suppressed by c-Myc and harnesses Myc-driven lymphomagenesis. ❋ Ulrich Keller (2010)

The study of intraclonal diversification (ID) in immunoglobulin (IG) genes offers valuable insight into the role of ongoing interactions with antigen in lymphomagenesis. ❋ E Kostareli (2010)

"Many of the genes involved in B-cell lymphomagenesis are normally regulated by signals from the B-cell antigen receptor, and the infectious agents could play a part by directly inducing polyclonal B-cell hyperactivation or providing a chronic antigenic stimulus," Jeong wrote. ❋ Unknown (2010)

Okumoto M, Yamate JA (2000) Susceptibility locus for radiation lymphomagenesis on mouse chromosome 16. ❋ Unknown (2009)

They found that, in mice engineered to overexpress c-Myc, also knocking out Puma accelerated lymphomagenesis.

Baudino TA, Maclean KH, Brennan J, Parganas E, Yang C, et al. (2003) Myc-mediated proliferation and lymphomagenesis, but not apoptosis, are compromised by E2f1 loss. ❋ Unknown (2009)

Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis. ❋ Unknown (2009)