Meglitinides

Studies show that the newest medicines like the thiazolidinediones, meglitinides, alpha glucosidase inhibitors, and the drug Januvia are not any more effective than those that have been around for decades, such as the sulfonylureas and metformin. ❋ Unknown (2009)

For this reason, people with type two diabetes can be treated with therapies that decrease insulin demand, including diet, exercise, and drugs; with medications that increase insulin supply, such as sulfonylurea or meglitinides or with insulin itself. ❋ Unknown (2008)

Certain diabetes medicines, such as sulfonylureas and meglitinides, can cause low blood sugar (hypoglycemia). ❋ Unknown (2009)

Parsing the risks and benefits in diabetes treatment is complicated by the fact that patients with diabetes receive a broad variety of drugs to help control blood sugar: In addition to metformin (Glucophage) and sulfonylureas, such as Diabinese and Glucotrol, there are the meglitinides, such as Prandin and Starlix, the thiazolidinediones, such as Avandia and Actos, alpha-glucosidase inhibitors such as Precose and Glyset, and the dipeptidyl peptidase-4 inhibitor Januvia (sitagliptin).

If you’re taking insulin or other drugs that cause you to make more insulin (such as sulfonylureas and meglitinides), you may be particularly prone to a hypoglycemic (low blood sugar) reaction to exercise. ❋ Bob Greene (2010)