One type is a flat, dark brown spot (a benign melanocytic nevus), another is pigmented and slightly raised (a junctional nevus), and there are also flesh-colored bumpy moles (intradermal nevi). ❋ Ellen Marmur (2009)
Robert Redford has intradermal nevi, Sarah Jessica Parker had a junctional nevus on her chin which recently was surgically removed, Cindy Crawford has a junctional nevus near her lip, and Marilyn Monroe had a very famous benign melanocytic nevus. ❋ Ellen Marmur (2009)
Benign melanocytic nevi show up on the skin naturally; and some—called congenital nevi—are evident at birth. ❋ Ellen Marmur (2009)
There are benign melanocytic nevi or normal moles, and dysplastic nevi, which have abnormal growth patterns. ❋ Ellen Marmur (2009)
Because the laser energy targets melanin in both the follicle and the skin, it can cause pigmentation problems for darker, more melanocytic complexions. ❋ Ellen Marmur (2009)
Ibrahim N, Haluska FG (2009) Molecular pathogenesis of cutaneous melanocytic neoplasms. ❋ Ara Parlakian Et Al. (2010)
O'Reilly FM, Brat DJ, McAlpine BE, Grossniklaus HE, Folpe AL, et al. (2001) Microphthalmia transcription factor immunohistochemistry: a useful diagnostic marker in the diagnosis and detection of cutaneous melanoma, sentinel lymph node metastases, and extracutaneous melanocytic neoplasms. ❋ Ara Parlakian Et Al. (2010)
It would also be appropriate to compare miRNA profiles from uncultured melanomas and melanocytic nevi with those presented here for purified pigment cells cultured in vitro, since the in vivo microenvironment might alter the relative abundance of some miRNAs, and conceivably condition whether some miRNAs are expressed. ❋ Mitchell S. Stark Et Al. (2010)
The sequenced libraries were selectively chosen as they represented an array of different melanocytic subtypes ranging from normal pigment cells (melanoblasts and melanocytes) to non-UV exposed (acral, mucosal and uveal), intermittently UV-exposed and chronically UV-exposed melanomas. ❋ Mitchell S. Stark Et Al. (2010)
Little is known about the repertoire and function of miRNAs in melanoma or the melanocytic lineage. ❋ Mitchell S. Stark Et Al. (2010)
