Microphthalmia

A major clinical and laboratory effort is ongoing in clinical and genetic aspects of congenital anophthalmia/microphthalmia. ❋ Unknown (2010)

Ongoing neuroradiology projects include orbital volumetric analysis of microphthalmia, orbital holography and functional MRI eyelid and orbital structures using special surface coils. ❋ Unknown (2010)

According to the Centers for Disease Control and Prevention, these eye defects, called anophthalmia and microphthalmia, occur in one out of 5,300 births in the U.S. About one out of 10,000 babies are born with amniotic band syndrome. ❋ Unknown (2011)

Carreira S, Liu B, Goding CR (2000) The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes. ❋ Ara Parlakian Et Al. (2010)

Hanniford D, Menendez S, Reavie L, Zou X, et al. (2009) Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor. ❋ Mitchell S. Stark Et Al. (2010)

The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C.collaborate to activate the tartrate-resistant acid phosphatase promoter by K.C. Mansky, G. Purdom, et al. Journal of Leukocyte Biology ❋ Unknown (2009)

The microphthalmia transcription factor (MITF) contains two N-terminal domains required for transactivation of osteoclast target promoters and rescue of mi mutant osteoclasts by K.C. Mansky, G. Purdom, et al. Journal of Leukocyte Biology ❋ Unknown (2009)