Misfolds

Word MISFOLDS
Character 8
Hyphenation N/A
Pronunciations N/A

Definitions and meanings of "Misfolds"

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Synonyms and Antonyms for Misfolds

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The word "misfolds" in example sentences

In the case of TTR amyloid polyneuropathy, a protein called transthyretin (TTR) "misfolds" and amyloid fibrils cluster in peripheral nerve tissues that serve limbs and organs. ❋ Unknown (2009)

When MstnPP-containing Escherichia coli inclusion bodies are refolded and purified, a proportion of MstnPP spontaneously misfolds into amyloid-like aggregates as characterised by electron microscopy and binding of the amyloid-specific dye thioflavin T. ❋ PLoS ONE (2010)

E. coli inclusion bodies, a population of MstnPP spontaneously misfolds into amyloid protofibril-like aggregates that can be visualised using electron microscopy and bind the amyloid-specific dye thioflavin T. ❋ Carlene S. Starck Et Al. (2010)

The fatal brain disease Creutzfeldt-Jakob in humans, BSE (bovine spongiform encephalopathy) in cattle and scrapie in sheep are so-called prion diseases, whereby one of the body's normal proteins, the prion protein PrPc misfolds into a pathogenic form: PrPSc. ❋ Unknown (2010)

In Parkinson's patients, the alpha-synuclein protein normally found in the brain misfolds, forming clumps. ❋ Unknown (2009)

C may wreak havoc in humans when it misfolds, but mice engineered to lack the protein have only a ❋ Unknown (2009)

In studying seven different proteins of the worm C. elegans, the researchers discovered that each protein misfolds at the same point: during early adulthood and long before the animal shows any behavioral, or physiological, change. ❋ Unknown (2009)

Alzheimer’s Disease starts when a protein that should be folded up properly misfolds into a kind of demented origami. ❋ Gregory Petsko (2008)

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