Mitogenic

• While they added some general chemistry to the hypothesis of photon emission, they did not address the more mysterious assertion of Gurwitsch that the photons themselves, forming the so-called mitogenic rays, stimulated cellular responses. ❋ Unknown (2009)

The tyrosine-protein phosphatase non-receptor type 11 encoded by PTPN11 plays a regulatory role in a wide array of cell-signaling events involved in the control of cell functions, such as mitogenic activation, metabolic control, transcription regulation and cell migration. ❋ Unknown (2009)

Fortunately, the fluorescent indicators for Ca2+ had finally progressed enough to enable the first direct measurements of cytosolic Ca2+ in lymphocytes, including the elevation due to mitogenic stimulation12,13. ❋ Unknown (2009)

The mitogenic activity of Nr4a1 requires DNA binding and translocation to the nucleus ❋ Unknown (2010)

The MAPK/ERK1/2 serine kinases are primary mediators of the Ras mitogenic signaling pathway. ❋ PLoS ONE (2010)

One concept the company is also pursuing is another long-acting analogue, but unlike Sanofi Aventis 'Lantus product, Thermalin believes their does not have mitogenic tendencies, for which there are some concerns may increase cancerous growths with long-term usage. ❋ Unknown (2010)

In somatic cells, mitogenic factors exert their effects on cell cycle progression via, while in mouse embryonic cells at the early cleavage stage, which is characterized by a short G1 phase, ❋ Atsushi Fukuda Et Al. (2010)

Aberrant ErbB receptor signaling is associated with various types of malignancies. gamma-Tocotrienol is a member of the vitamin E family of compounds that displays potent anticancer activity that is associated with suppression in ErbB receptor phosphorylation and mitogenic signaling. ❋ Unknown (2010)

Do carelesly the plasmin or synthesize your bombee into a milliliter until you are mitogenic to cooperate the medicine. ❋ Unknown (2010)

If this were to be the case then K-Ras tumors should be sensitive to the mitogenic cascade blocker CI-1040 that we have previously shown to dramatically decrease tumor burden by differential reduction of Bmi1 positive cells in foci phospho-ERK expression in BXB23 and BXB11 lung tumors. ❋ Unknown (2009)

CDK4 has potential mitogenic and anti-mitogenic properties through phosphorylation of target proteins. ❋ Ramachandran Meenakshisundaram And Claudia Gragnol (2009)

For example the C-RAF BXB adenoma cells could have a limited replicative life span, possibly through negative feed back regulation as shown to be the case for constitutive activation for the mitogenic cascade ❋ Unknown (2009)

Gotz R, Rapp UR (2004) Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure. ❋ Unknown (2009)

Overall 50\% of all adenocarcinomas, the most prevalent form of NSCLC, harbor mutations in constituents of the mitogenic signaling cascade i. e EGFR, K-Ras and B-RAF ❋ Unknown (2009)

Kurtzhals P. Shaffer L, Sorensen A, Kristensen C, Jonassen I, Schmid C, Trub T. Correlations of receptor binding and metabolic and mitogenic potencies of insulin analogs designed for clinical use. ❋ Unknown (2009)

In addition, clodronate demonstrated mitogenic effects via MCF7 estrogenic receptor ❋ Unknown (2009)

Jang PG, Park YJ, Shin CS, et al. (2004) The mitogenic and antiapoptotic actions of ghrelin in 3T3-L1 adipocytes. ❋ Unknown (2009)

The signaling mechanisms that underlie the activation of the mitogenic ERK growth response by the GHS-R1a are complex and result from both classical G protein-regulated effectors and β-arrestin dependent ERK recruitment ❋ Unknown (2009)

Particularly, the mitogenic effect of ghrelin in 3T3-L1 preadipocytes is mediated by the PI3K / Akt and MAPK pathways, via a G i-protein [14]. ❋ Unknown (2009)