The drug, Edurant, belongs to a class of HIV drugs called non-nucleoside reverse transcriptase inhibitors and works to block HIV viral replication. ❋ Jennifer Corbett Dooren (2011)
All three drugs are known as non-nucleoside reverse transcriptase inhibitor drugs, or NNRTIs. ❋ Unknown (2007)
- 1995: Two new classes of anti-HIV drugs, also targeting replication, are approved: protease inhibitors and non-nucleoside reverse transcriptase inhibitors. ❋ Unknown (2006)
There are three classes of these drugs: protease inhibitors, nucleoside reverse transcriptase inhibitors and non-nucleoside transcriptase inhibitors. ❋ Unknown (2005)
Conferees are also discussing the development of strains that are particularly resistant to treatment as well as the hope presented by new treatments, such as the non-nucleoside reverse transcriptase inhibitor. ❋ Unknown (2002)
Antiretroviral regimens for HIV-1 that included non-nucleoside reverse transcriptase inhibitors NNRTIs, zidovudine, stavudine or didanosine were not permitted.
Regarding the combined tablets' program, recent news announced that a single tablet combining Gilead's Truvada (tenfovir/emtricitabine) with its collaborator Tibotec's non-nucleoside reverse transcriptase inhibitor Edurant (rilpivirine) is currently under review by
TMC-278 is a non-nucleoside reverse transcriptase inhibitor that prevents a key enzyme of the AIDS virus from converting its RNA to DNA and stops the virus from infecting cells.
Two of these studies were conducted in clinically advanced, three-class ARV non-nucleoside reverse transcriptase inhibitor (NNRTI), nucleoside reverse transcriptase inhibitor (NRTI), protease inhibitor (PI) treatment-experienced adults and one was conducted in treatment-naïve adults.
The drug, a non-nucleoside reverse transcriptase inhibitor, is intended to treat HIV in adults who have not used another therapy. ❋ Unknown (2011)
The HIV medicines evaluated in these studies included ritonavir, ritonavir-boosted protease inhibitors, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) and a nucleotide analogue reverse-transcriptase inhibitor (NRTI).
Genelabs Technologies today announced that a non-nucleoside compound from its internal Hepatitis C v ... ❋ Editors (2010)
Although protease inhibitors specifically designed to inhibit HIV-encoded protease do not affect XMRV infection and replication, nor do non-nucleoside reverse-transcriptase inhibitors (NNRTI), XMRV is susceptible to the nucleoside reverse-transcriptase inhibitors (NRTI) azidothymidine (AZT) but not tenofovir in one study ❋ Marion Cornelissen Et Al. (2010)
Tibotec's drug, TMC-278, is a non-nucleoside reverse transcriptase inhibitor that prevents a key enzyme of the AIDS virus from converting its RNA to DNA and stops the virus from infecting cells. ❋ Unknown (2010)
Truvada - itself a combination of Gilead's Viread and Emtriva HIV treatments that was introduced in August 2004 - is part of the nucleoside class of HIV drugs and is taken with a lineup of complementary non-nucleoside reverse transcriptase inhibitors. ❋ Unknown (2010)
VX-222 is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase. ❋ Pillscribe (2010)
