Four novel nonsynonymous mutations were detected, one of which would produce premature termination of translation c.2686CT p. ❋ Unknown (2007)
As a longtime sometime magician, I want to point out that distraction and misdirection are overlapping but nonsynonymous. ❋ Unknown (2006)
They measured the fitness effect of the mutations as a ratio between synonymous (Ks) and nonsynonymous (Ka) amino acid substitutions (so they sequenced 13 mitochondrial genes and counted substitutions). ❋ Unknown (2006)
Missense mutations or nonsynonymous mutations is where a nucleotide is changed which results in a different amino acid. ❋ Unknown (2005)
WDFY4 is a huge protein with unknown function but is predominantly expressed in primary and secondary immune tissues, and a nonsynonymous SNP in this gene was found to be highly associated with SLE susceptibility. ❋ Razib Khan [email protected] (2010)
Sunyaev S, Hanke J, Aydin A, Wirkner U, Zastrow I, et al. (1999) Prediction of nonsynonymous single nucleotide polymorphisms in human disease-associated genes. ❋ Sungsam Gong Et Al. (2010)
Bickerton GR, Schreyer A, Forman JR, Cheng TM, et al. (2007) A structural bioinformatics approach to the analysis of nonsynonymous single nucleotide polymorphisms (nsSNPs) and their relation to disease. ❋ Sungsam Gong Et Al. (2010)
Moreover, we identified that plasmid conjugative transfer genes and antibiotic resistance genes are more likely to suffer from positive selection, as indicated by the elevated rates of nonsynonymous substitution. ❋ PLoS ONE (2010)
These are contrasted to synonymous SNPs (black) and nonsynonymous SNPs (white) in left histogram, to 1 bp insertions (black) and 1 bp deletions ❋ Per Sjödin Et Al. (2010)
For each transmission pair, selection within individuals was quantified using the ratio of nonsynonymous to synonymous substitutions (ω = dN/dS). ❋ Hong Zhang Et Al. (2010)
An automated routine identifying human nonsynonymous SNP amino acid missense substitutions for any MHC gene mined the NCBI SNP data base. ❋ Unknown (2010)
Since some models allow the incorporation of heterogeneous ω ratios (the ratio of nonsynonymous to synonymous substitutions per site) among amino acid sites, it is possible then to infer which sites are under selection using a Bayesian method. ❋ Karen Luisa Haag Et Al. (2009)
To focus the analysis on the putative antigenic diversity (i.e. polymorphisms that change protein structure) the nonsynonymous single nucleotide polymorphism (nsSNP) haplotypes were derived for all antigen sequences, except for msp1, for which the majority of the data comprised only a 5 amino acid haplotype ❋ Alyssa E. Barry Et Al. (2009)
SNPs, though only one was a standard change in amino acid coding (nonsynonymous mutation). ❋ Unknown (2009)
Broughton RE, Reneau PC (2006) Spatial covariation of mutation and nonsynonymous substitution rates in vertebrate mitochondrial genomes. ❋ Melanie Norgate Et Al. (2009)
Furthermore, combining our demographic model with a previously estimated distribution of selective effects among newly arising amino acid mutations accurately predicts the frequency spectrum of nonsynonymous variants across three continental populations (YRI, CHB, CEU). ❋ Unknown (2009)
This finding is consistent with the observation of elevated nonsynonymous substitution rates within higher lineage specificity groups, such as comparisons between an ❋ Takao Kasuga Et Al. (2009)
In Caucasians, one nonsynonymous SNP in FUT2 (G428A, rs601338) accounts for > ❋ Unknown (2009)
Allele identification of the one nonsynonymous SNP in FUT2 that accounts for > ❋ Unknown (2009)
