Microbes using this infection mechanism include fungi that are currently causing wheat rust epidemics in Africa and Asia, and a class of parasitic algae, called oomycetes, that resulted in the Irish potato blight of the 19th Century. ❋ Unknown (2010)
Fungi and fungal-like microbes known as oomycetes produce effector molecules that penetrate cells and switch off the host's defense system. ❋ Unknown (2010)
The researchers also found evidence suggesting that fungi and oomycetes might infect humans and animals through the same newly-discovered mechanism as they use to infect plants. ❋ Unknown (2010)
By contrast, the mechanism used by fungi and oomycetes -- neither of which have an injection apparatus -- to slip their effectors into plant cells had not been previously identified before. ❋ Unknown (2010)
The novelty and simplicity of the mechanism used by fungi and oomycetes to insert their effectors into host cells. ❋ Unknown (2010)
The discovery that fungi and oomycetes use the same binding mechanism to introduce effectors into plant cells, even though these two classes of microbes are evolutionarily distinct from one another. ❋ Unknown (2010)
This finding opens new potential avenues for developing therapies for fighting diseases caused by fungi and oomycetes. ❋ Unknown (2010)
It was previously known that some bacteria, fungi and oomycetes infect plants by slipping effectors that disable immune systems into plant cells. ❋ Unknown (2010)
In addition, in water environments, oomycetes cause destructive diseases in people and animals. ❋ Unknown (2010)
Also, the binding lipid used by the effectors of fungi and oomycetes had never before been detected on cell surfaces (although it had been detected inside cells). ❋ Unknown (2010)
"This is a great example of transdisciplinary research, pulling together researchers from around the world with expertise in oomycetes, fungi, human disease and lipid chemistry," explains the lead author of the work, VPI graduate student Shiv Kale. ❋ Unknown (2010)
The project has a conceptual scope of all plant pathogens, with an initial focus on fungi and oomycetes. ❋ Unknown (2010)
O'Connell RJ, Panstruga R (2006) Tete and tete inside a plant cell: establishing compatibility between plants and biotrophic fungi and oomycetes. ❋ Sumanti Gupta Et Al. (2010)
Kamoun S (2006) A catalogue of the effector secretome of plant pathogenic oomycetes. ❋ Unknown (2009)
For oomycetes, the identification of the first Avr genes led to the discovery of new protein targeting motifs that deliver effectors into host cells ❋ Unknown (2009)
Bremia, Peronospora, Phytophthora, and Pythium cause well-known diseases, but not all oomycetes are plant pathogens. ❋ Unknown (2009)
The oomycetes resemble fungi in many respects but have evolved independently and are classified separately, in the Stramenopila. ❋ Unknown (2009)
Bos J, Krasileva KV, Cano LM, et al. (2007) Adaptive evolution has targeted the C-terminal domain of the RXLR effectors of plant pathogenic oomycetes. ❋ Unknown (2009)
