DFMO is an inhibitor that specifically targets a key protein called ornithine decarboxylase ❋ Unknown (2010)
The most common of the disorders is called ornithine transcarbamylase deficiency (OTC), with a prevalence of around one in 30,000, said Dr. Mark Batshaw, principal investigator of the Urea Cycle Disorders Consortium, part of the NIH's Office of Rare Diseases Research Network. ❋ Unknown (2010)
Such issues include Jesse Gelsinger20 suffered from a rare genetic disorder called ornithine transcarbamylase de fi - exotic therapies versus cheaper more widely ciency, which, while requiring cumbersome treat - useful therapies; ment with diet and drugs, was not a life-threatening disorder for him. ❋ Martins0105 (2009)
Aminoacidopathies (maple syrup urine disease; homocystinuria; cobalamin deficiencies; tyrosinemia; urea cycle defects (ornithine transcarbamylase, carbamyl phosphate synthase, citrullinemia, argininosuccinic aciduria, arginase deficiencies) and non-ketotic hyperglycinemia) ❋ Unknown (2010)
Jesse was participating in a gene therapy trial for ornithine transcarboxylase deficiency (OTCD). ❋ Unknown (2008)
It stimulates your release of growth hormone and ornithine decarboxylase enzymes. ❋ Palahniuk, Chuck (2003)
The major immune system and human growth hormone stimulants are the amino acids lysine, arginine, and ornithine. ❋ Ph.D. Richard A. Passwater (1991)
D. Dakin he investigated arginase, the ferment which hydrolyses arginine into urea and ornithine, and later he discovered agmatine in herring roe and devised a method for preparing it. ❋ Unknown (1967)
I did not know this when I was fasting John, but now, I would give argenine and ornithine to someone with a serious infection as well as massive quantities of vitamin C. ❋ Isabel Moser (N/A)
The precursors are two essential amino acids, argenine and ornithine and certain vitamins such as C and B6. ❋ Isabel Moser (N/A)
Growth hormone is only manufactured under certain, specific circumstances: for about one hour immediately after going to sleep and then only if the blood supply is rich with argenine and ornithine but contains few other amino acids; it is also manufactured during heavy aerobic exercise that goes on for more than thirty minutes; and growth hormone is produced at an accelerated rate when fasting. ❋ Isabel Moser (N/A)
This is a sign of a genetic disorder called OTC ornithine transcarbamylase deficiency. ❋ Cherrill Hicks (2012)
The study includes infants, toddlers and children up to the age of five, who are suffering from the most severe forms of the following UCDs: ornithine transcarbamylase (OTC) deficiency, carbamoyl-phosphate synthetase I (CPS I) deficiency or argininosuccinate-synthetase (ASS) deficiency, also called citrullinemia. ❋ Unknown (2010)
However, in mammalian non-hepatic tissues, the main use of the urea cycle are in arginine biosynthesis, so as an intermediate in metabolic processes, ornithine is quite important. ❋ Amp;34; (2010)
Previously, we identified ZNF9 in a screen for proteins binding to an IRES element from the rat ornithine decarboxylase (ODC) mRNA ❋ Morgan A. Sammons Et Al. (2010)
Previously, our group identified ZNF9 as a positive regulator of IRES-mediated translation for the rat ornithine decarboxylase (ODC) mRNA trans-activating factor (ITAF) for cap-independent translation of the human ODC mRNA. ❋ Morgan A. Sammons Et Al. (2010)
Few people are really deficient in ornithine, unless they are extremely malnourished or have a disorder that disrupts the citric acid cycle; however, if you wish to try ornithine supplementation for the purpose of increasing your body's muscle content, or to fight the effects of aging, you can purchase supplemental ornithine capsules or powders at your local health food store and, in many cases, your local pharmacy. ❋ Unknown (2010)
