Orthologs

The following protein pairs could be unambiguously identified as orthologs on the basis of common domain architecture and high sequence identity: (A) C34F11. 9a / DVL2, (B) ❋ Unknown (2008)

For comparison, we also gathered the closest non-orthologs, meaning sequences close in sequence space, yet falling just outside the ortholog cluster. ❋ Anna Henricson (2010)

We might still be able to distinguish between orthologs and paralogs, as a matter of logical principle but, in practice, this will often be impossible. ❋ Unknown (2009)

The conservation was defined based on an alignment window of +/- 10AAs of S. cerevisiae proteins against orthologs in C. albicans, S. pombe, D. melanogaster and H. sapiens. ❋ Pedro Beltrao (2009)

But it * is* mentioned that orthologs and paralogs of these genes gave rise in later metazoan evolution to other components of other types of nerve cell junctions. ❋ Unknown (2007)

To illustrate how easy it is to use it I have built a Kapow robot to get, for any human geneID, a list of orthologs with species and IDs. ❋ Pedro Beltrao (2007)

The evolutionary analysis was aided by sequencing the entire coding region of CARD15 in three primates chimp, gibbon, and tamarin and aligning the human sequence with these and orthologs from other species. ❋ Unknown (2007)

From here there are a set of loops and conditional statements that you can include to get the list of orthologs: ❋ Pedro Beltrao (2007)

For example, whereas in urochordates the ancestral Hox cluster has fragmented, the individual genes show high levels of sequence identity and similar A/P-restricted patterns of expression to their orthologs in other bilaterians. ❋ Unknown (2006)