Penicillinase

An example would be the bacteria that secrete penicillinase, which is an enzyme that destroys penicillin. ❋ Blish, James (1957)

Recall that Axe did not work with the native TEM-1 penicillinase, but rather with a variant that had a lower activity. ❋ Unknown (2007)

The object of interest was the so-called large domain of the TEM-1 penicillinase, an enzyme that breaks down antibiotics related to penicillin. ❋ Unknown (2007)

Therefore it is necessary to treat breast infections with a penicillinase-resistant antibiotic such as either flucloxacillin or erythromycin. ❋ Unknown (1997)

- Antibacterial (antibiotic) of the penicillin group, acting specifically against penicillinase producing staphylococci ❋ Unknown (1993)

Since 1948 his research topics have included carbohydrate-amino acid relationship in nervous tissue, a study of the mode of action of insulin, fermentation technology, 6-aminopenicillanic acid and penicillinase-stable penicillins, lysergic acid production in submerged culture, and the isolation of new fungal metabolites. ❋ Unknown (1964)

C. Resistance to penicillin is mediated both by plasmid-encoded penicillinase and by changes in chromosome-encoded proteins that control the permeability of the drug. ❋ Crisbertc (2009)

Staphylococcus aureus (MRSA), resulting in the concept that MRSA has emerged on a few occasions after penicillinase-stable β-lactam antibiotics were introduced to clinical practice, followed by intercontinental spread of individual clones. ❋ Unknown (2008)

Axe’s numbers tell us about the apparent isolation of the low-activity variant, but reveal little nor can it be expected to about the “isolation” or evolution of TEM-1 penicillinase. ❋ Unknown (2007)

Before I discovered I wasn't cut out to be a bench biochemist, my undergraduate research was on "Competitive inhibition of penicillinase by notalysin, a ❋ Unknown (2008)