Phosphodiesterases

Generic Viagra Sildenafil Citrate belongs to a group of medicines that delay the enzymes called phosphodiesterases from working too quickly. ❋ MN Politics Guru (2007)

Cyclic AMP, the neurotransmitter that dictates CREB levels, is normally degraded in the brain by enzymes called phosphodiesterases. ❋ Unknown (2007)

For instance, enzymes such as phospholiphases, phosphodiesterases and proteases of various nature, which by themselves may lack specific recognition sites in target cells, may exploit ❋ Unknown (1986)

However, we hypothesised that release of BP7033Br ALK with free phosphonic group could be more important in in vivo system because of the presence of phosphodiesterases in serum. ❋ Unknown (2009)

In previous work, Insel's group had discovered that among a group of enzymes, cyclic nucleotide phosphodiesterases, one of the phosphodiesterases, PDE7B, was 10 times higher in CLL patients than in healthy individuals. ❋ Unknown (2009)

These phosphodiesterases have additional specificity for ❋ Unknown (2008)

This invention pertains to the discovery that L-arginine type V phosphodiesterases act synergistically to inhibit vasospasm and / or to induce vasodilation. ❋ Unknown (2008)

MN-166 increases the release of neuronal growth factors and inhibits leukotriene activity, phosphodiesterases and nitric oxide synthase. ❋ Unknown (2008)

This is accomplished primarily by phosphodiesterases ❋ Unknown (2008)

Unlike most GAF domain-containing cyclic nucleotide phosphodiesterases, little is known about direct allosteric communication of PDE6. ❋ X.-J. Zhang (2008)

Watanabe S (2001) Regulatory roles of adenylate cyclase and cyclic nucleotide phosphodiesterases 1 and 4 in interleukin-13 production by activated human T cells. ❋ Unknown (2008)