AVI-7100 employs the Company's patented PMOplus™ technology that selectively introduces positive charges to a phosphorodiamidate morpholino oligomer PMO backbone to improve selective interaction between the drug and its target.
AVI's proprietary, intrinsically charge-neutral, phosphorodiamidate morpholino oligomer PMO ❋ Unknown (2011)
The drugs are in a class of compound called PMO, for phosphorodiamidate morpholino oligomers. ❋ Unknown (2010)
Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists conducted studies in which nine rhesus monkeys were challenged with lethal Ebola virus, reports ❋ Unknown (2010)
Working with a class of compounds known as antisense phosphorodiamidate morpholino oligomers, or PMOs, scientists first performed a series of studies with mouse and guinea pig models of Ebola to screen various chemical variations. ❋ Unknown (2010)
AVI BioPharma is focused on the discovery and development of RNA-based medicines utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action. ❋ Unknown (2010)
AVI BioPharma is focused on the discovery and development of RNA-based therapeutics utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action. ❋ Unknown (2010)
AVI BioPharma is focused on the discovery and development of RNA-based drugs utilizing proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action. ❋ Unknown (2010)
Writing in the journal Nature Medicine, Sina Bavari and colleagues said the drugs tested are antisense phosphorodiamidate morpholino oligomers, or PMOs, called AVI-6002 and ❋ Unknown (2010)
The collaboration will support a series of GLP toxicology studies for AVI's exon skipping drug candidates based on phosphorodiamidate morpholino oligomers (PMO) chemistry. ❋ Unknown (2009)
AVI BioPharma is focused on the discovery and development of RNA - based drugs utilising proprietary derivatives of its antisense chemistry (morpholino-modified phosphorodiamidate oligomers or PMOs) that can be applied to a wide range of diseases and genetic disorders through several distinct mechanisms of action. ❋ Unknown (2008)
