Character 11
Hyphenation N/A
Pronunciations N/A

Definitions and meanings of "Presynaptic"

What do we mean by presynaptic?

Situated in front of or occurring before a synapse. adjective

In a synapse, of or pertaining to the neuron that releases neurotransmitter into the synaptic cleft adjective

In a synapse, of or pertaining to the neuron that releases neurotransmitter into the synaptic cleft.

Synonyms and Antonyms for Presynaptic

  • Synonyms for presynaptic
  • Presynaptic synonyms not found!!!
  • Antonyms for presynaptic
  • Presynaptic antonyms not found!

The word "presynaptic" in example sentences

The lack of an effect of the serine-413 mutation of RIM1α is not due to compensation by RIM2α because mice carrying both the serine-413 substitution and a RIM2α deletion still exhibited normal long-term presynaptic plasticity. ❋ P. S. Kaeser (2008)

Thus, phosphorylation of serine-413 of RIM1α is not essential for PKA-dependent long-term presynaptic plasticity ❋ P. S. Kaeser (2008)

Locally it blocks the initiation and propagation of nerve impulses along an axon by interference with sodium permeability during depolarization. 3,11 Centrally it blocks the presynaptic reuptake of norepinephrine and dopamine. ❋ Unknown (2010)

Synthesis and storage of neurotransmitter in the presynaptic knob of axon ❋ Unknown (2008)

Generally, neurotoxins affecting neurotransmission act to increase or decrease the release of a neurotransmitter at the presynaptic membrane, block receptors at the postsynaptic membrane, or modify the inactivation process of the neurotransmitter. ❋ Unknown (2008)

Platelet bioamines in blood, urine or saliva for NE norepinephrine, Dopamine and Serotonin, Melatonin, Acetylcholine, GABA should reflect NMDA induction and depletion of presynaptic inhibitory neurotransmitters. ❋ Unknown (2008)

Given that neurons 'activity depends partly upon their total input, and total input depends partly on synaptic weights (e.g., presynaptic neurotransmitter release rate, number and efficacy of postsynaptic receptors, availability of enzymes in synaptic cleft), the capacity of biological networks to change their synaptic weights make them plastic vector-to-vector transformers. ❋ Bickle, John (2006)

At electrical synapses, the current generated by the action potential at the presynaptic neuron flows directly into the postsynaptic cell, which is physically connected to the presynaptic terminal by a so-called gap junction. ❋ Atmanspacher, Harald (2006)

For example, Eric Kandel (1976) proposed presynaptic mechanisms governing transmitter release rate as a cell-biological explanation of simple forms of associative learning. ❋ Bickle, John (2006)

There are presynaptic dopaminergic receptors which, when stimulated by dopamine, inhibit its own release. ❋ Unknown (2006)

Dopamine release in the prefrontal cortex also seems to facilitate GABA inhibition, possibly by way of presynaptic facilitation of transmitter release, leading to a further reduction of excitation through prefrontal circuits. ❋ Steven Johnson (2004)

Because cells in the retina of one eye are more likely to fire spontaneously at the same time, and are much less likely to fire at the same time as cells in the other eye, chances are that when a postsynaptic cortical cell is activated by presynaptic inputs from one eye, presynaptic inputs from other cells in the same eye will be arriving more or less simultaneously. ❋ Steven Johnson (2004)

One possible way to make sense of this is that at various synaptic fields, serotonin release is also controlled by local presynaptic mechanisms i.e., via axo-axonic synapses. ❋ Steven Johnson (2004)

Why such complexity exists on the postsynaptic side, with comparative simplicity at the presynaptic side, remains perplexing. ❋ Steven Johnson (2004)

Cross Reference for Presynaptic

  • Presynaptic cross reference not found!

What does presynaptic mean?

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