Proneural

Of the 24 methylated tumors, 21 fell in the "proneural" signature in which the genes expressed are associated with neural development. ❋ Unknown (2010)

Our genetic evidence from Drosophila and previous in vitro studies of mammalian Atonal homolog 1 (Atoh1, also called Math1 or Hath1) suggest an anti-oncogenic function for the Atonal group of proneural basic helix-loop-helix transcription factors. ❋ Matthew Guerrieri (2009)

It's a proneural gene, which means it activates some part of the embryonic development of the nervous system — in this case, chordotonal organs, cell structures designed to pick up vibrations (think eardrums and the like). ❋ Matthew Guerrieri (2009)

Carmena A, Bate M, Jimenez F (1995) Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis. ❋ Sarada Bulchand Et Al. (2010)

Mash1 is a proneural transcription factor of the basic helix-loop-helix family, which participates in the commitment of neural progenitors, promotion of cell cycle exit and neuronal migration, and in the final specification of neuronal identities in the brain ❋ Hortensia Sanchez-Calderon Et Al. (2010)

The proneural bHLH transcription factor Mash1 was also more strongly expressed in the auditory nerve (AN) of the E18. 5 ❋ Hortensia Sanchez-Calderon Et Al. (2010)

Hath1) suggest an anti-oncogenic function for the Atonal group of proneural basic helix-loop-helix transcription factors. ❋ Unknown (2009)