Pseudogenes

Mutations in pseudogenes do not suggest they are functional. ❋ Unknown (2007)

Yet another argument for the common ancestry of chimps and humans comes from the peculiar observation of what are called pseudogenes. ❋ Francis S. Collins (2006)

Gene families have arisen from duplication over time, containing silenced genes (sometimes called pseudogenes). ❋ Rheinberger, Hans-Jörg (2009)

These chromosomal regions could be composed of the now-defunct remains of ancient genes, known as pseudogenes, which were once functional copies of genes but have since lost their protein-coding ability and, presumably, their biological function. ❋ Unknown (2007)

What many have forgotten is that Ohno was commenting on a particular form of ‘junk’ namely pseudogenes and the term “Junk DNA” slowly took on a different meaning to include all non-coding sequences sequences that do not produce proteins. ❋ Unknown (2007)

When Ohno published his famous paper in 1972, he focused his attention mainly on the fossilized genes, called pseudogenes, that are strewn like tombstones throughout our DNA. ❋ Unknown (2007)

The new findings suggest that nature has crafted a clever tale of espionage such that thousands upon thousands of mRNAs and noncoding RNAs, together with a mysterious group of genetic relics known as pseudogenes, take part in undercover reconnaissance of cellular microRNAs, resulting in a new category of genetic elements which, when mutated, can have consequences for cancer and human disease at large. ❋ Unknown (2010)

Although most retroposition events result in non-functional duplicates (called pseudogenes), in rare cases, retroposed genes, like Rps23r1, can become functional. ❋ Unknown (2009)

Of course, there are some sequences, such as pseudogenes and damaged endoviral remnants, that are strong candidates for identification as junk, but even there one must be cautious, because evolutionary theory predicts that in some cases new functions will be found for such “left over” sequences. ❋ Unknown (2007)

Claim: Darwinian theory explains the existence of vestigial organs or ‘junk DNA’ such as pseudogenes ❋ Unknown (2006)

Over the course of evolution, they have decayed into functionless 'pseudogenes', now nothing more than genetic garbage. ❋ Unknown (2010)

Summary: During the Dover trial, Ken Miller testified supporting evolution by discussing the presence of "pseudogenes" in humans and other organisms. ❋ Unknown (2009)

Which means that the ancestral RNase genes were not pseudogenes that evolved functions, but vice versa, proteins with functions that became pseudogenes in some lineages. ❋ Unknown (2009)

If non-functional DNA is quickly transformed into gibberish, why do chimps and humans still have these remarkably similar pseudogenes? ❋ Unknown (2009)