Pyknotic

"I think that this pyknotic theory of substance will prove more acceptable to every biologist who is convinced of the unity of nature than the kinetic theory which prevails in physics to-day" ❋ Oliver Lodge (1895)

Moreover, the number of osteoclasts increased as the cumulative dose of of these osteoclasts were giant cells with pyknotic nuclei that were adjacent to superficial resorption cavities. ❋ Unknown (2009)

Top graph: in every case except for NO, at a given concentration / level of the indicated treatment, and at the time points examined, on average, less than half as many nuclei in neurons over-expressing ZEB1 showed a shrunken / pyknotic / condensed morphology compared with their GFP-expressing counter-parts. ❋ Unknown (2009)

GFP-positive neurons were processed and scored (in a blinded fashion) for having either a normal vs a pyknotic / mis-shapen / condensed morphology. ❋ Unknown (2009)

Sixteen hours later, cells from both groups were subjected to OGD for 6 hrs, fixed under hypoxia, the nuclei were Hoechst-stained and then scored (in a blinded fashion) for presence of either a normal vs pyknotic / mis-shapen / condensed morphology. ❋ Unknown (2009)

Over twice as many pyknotic nuclei were scored in ZEB KO cells as compared to their wt counterparts. ❋ Unknown (2009)

"I must lay down the following theses, which are involved in Vogt's pyknotic theory, as indispensable for a truly monistic view of substance, and one that covers the whole field of organic and inorganic nature: -- ❋ Oliver Lodge (1895)

Figure 3, top; and S3), parallel cultures were stained with Hoechst 33342 dye (Molecular Probes / Invitrogen) and neurons with pyknotic / shrunken / fragmented nuclei (a hallmark of dying cells) as compared with "healthy" nuclei (normal, rounded morphology, indistinguishable from untreated control cells) were scored in a similar fashion as with the mitochondrial dye. ❋ Unknown (2009)