Favia uses docking to recognize interesting substrates for short-chain dehydrogenases/reductases. ❋ Egon Willighagen (2008)
Escherichia coli required the presence of the natural reductases for full enzymatic activity. ❋ PLoS ONE (2010)
Jornvall H, Persson B, Krook M, Atrian S, Gonzalez-Duarte R, et al. (1995) Short-chain dehydrogenases/reductases (SDR). ❋ Matthias Negri Et Al. (2010)
Herein, we present the first, to our knowledge, computational investigation of the kinetic mechanism of 17β-HSD1, one of the thirteen 17β-HSDs belonging to the short-chain dehydrogenases/reductases (SDR), a large superfamily of NAD (P) H-dependent enzymes. ❋ Matthias Negri Et Al. (2010)
A difference in enzymes (reductases) is responsible for the different E and Z ratios ❋ Unknown (2010)
Intriguingly, there are many differences in the amino acid sequences of the reductases isolated from the E or Z races. ❋ Unknown (2010)
This combination of abundant cytochromes with weak sequence conservation suggests they may not be specific terminal reductases, but rather may be important in their heme-bearing capacity, as sinks for electrons between the inner-membrane electron transport chain and the extracellular acceptor. ❋ Jessica Butler (2010)
However, an impairment of methionine sulfoxide reductases surveillance function, as on ageing, would allowed the accumulation of oxidized proteins, as the aberrantly folded PrP ❋ Unknown (2009)
Consequently an optimal function of methionine sulfoxide reductases would be required not only for repairing damaged proteins but also for engaging in a cycle of methionine oxidation and reduction that ultimately would results in the scavenging of reactive oxygen species. ❋ Unknown (2009)
(These detoxifying enzymes include quinone reductases and glutathione-S-transferases). ❋ Unknown (2009)
(These detoxifying enzymes include the quinone reductases and glutathione-S-transferases). ❋ Unknown (2009)
Glutaredoxins (Grxs) are efficient catalysts for the reduction of mixed disulfides in glutathionylated proteins, using glutathione or thioredoxin reductases for their regeneration. ❋ J. Couturier (2009)
- JoAnne Stubbe, for her experiments that established the mechanisms of ribonucleotide reductases, polyester synthases and natural product DNA cleavers. ❋ Unknown (2009)
Marchetti MA, Pizarro GO, Sagher D, Deamicis C, Brot N, et al. (2005) Methionine sulfoxide reductases B1, B2, and B3 are present in the human lens and confer oxidative stress resistance to lens cells. ❋ Maria Marchetti Et Al. (2009)
Moskovitz J (2005) Methionine sulfoxide reductases: ubiquitous enzymes involved in antioxidant defense, protein regulation, and prevention of aging-associated diseases. ❋ Maria Marchetti Et Al. (2009)
Weissbach H, Resnick L, Brot N (2005) Methionine sulfoxide reductases: history and cellular role in protecting against oxidative damage. ❋ Maria Marchetti Et Al. (2009)
